Gene Ontology (GO)
OWL
Last submission date March 22, 2025
ID http://purl.obolibrary.org/obo/GO_0016987
http://purl.obolibrary.org/obo/GO_0016987
https://agroportal.lirmm.fr/ontologies/GO/GO_0016987
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Preferred name

sigma factor activity

Synonyms
DNA-dependent RNA polymerase promoter selection factor sigma transcription factor core DNA-dependent RNA polymerase binding promoter specificity activity bacterial sigma factor activity plastid sigma factor activity promoter selection factor activity
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Definitions
Sigma factors act as the promoter specificity subunit of eubacterial and plant plastid multisubunit RNA polymerases, whose core subunit composition is often described as alpha(2)-beta-beta-prime. Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, the sigma factor binds specifically to promoter elements. The sigma subunit is released once elongation begins.
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