CL | Classes | AgroPortal

ID	http://purl.obolibrary.org/obo/PR_000001012 http://purl.obolibrary.org/obo/PR_000001012 Loading
Preferred name	integrin alpha-M
Synonyms	CD11b
Definitions	Category=gene. Requested by=CL.

rdfs:comment	Category=gene. Requested by=CL.
rdfs:comment	Category=gene. Requested by=CL.
oboinowl_gen:hasDbXref	IUPHARobj:2452
obo_purl:IAO_0000115	An integrin alpha with A domain that is a translation product of the human ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1.
skos:notation	PR:000001012
oboinowl_gen:hasExactSynonym	CD11b cell surface glycoprotein MAC-1 subunit alpha neutrophil adherence receptor ITGAM CR-3 alpha chain CD11 antigen-like family member B leukocyte adhesion receptor MO1
oboinowl_gen:hasOBONamespace	protein
rdf:type	http://www.w3.org/2002/07/owl#Class
oboinowl_gen:hasRelatedSynonym	CR3A CD11B
oboinowl_gen:id	PR:000001012
rdfs:label	integrin alpha-M
rdfs:subClassOf	http://purl.obolibrary.org/obo/PR_000001005

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