Cell Ontology (CL)
OWL
Last submission date April 8, 2024
ID http://purl.obolibrary.org/obo/PR_000001002
http://purl.obolibrary.org/obo/PR_000001002
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Preferred name

CD19 molecule

Synonyms

differentiation antigen CD19

Definitions

A protein that is a translation product of the human CD19 gene or a 1:1 ortholog thereof. It is composed of an N-terminal extracellular domain containing two Ig-like C2-type (immunoglobulin-like) domains, followed by a single-pass transmembrane segment and a cytoplasmic C-terminal tail. CD19 expression is restricted to members of the B cell lineage. It functions as a co-receptor for B-cell antigen receptor (BCR), regulating signal transduction.

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