Cell Ontology (CL)
OWL
Last submission date April 8, 2024
ID http://purl.obolibrary.org/obo/GO_0042101
http://purl.obolibrary.org/obo/GO_0042101
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Preferred name

T cell receptor complex

Synonyms

T-cell receptor complex

Definitions

A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily, and mediates antigen recognition, ultimately resulting in T cell activation. The TCR heterodimer is associated with the CD3 complex, which consists of the nonpolymorphic polypeptides gamma, delta, epsilon, zeta, and, in some cases, eta (an RNA splice variant of zeta) or Fc epsilon chains.

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