Cell Ontology (CL)
OWL
Last submission date May 15, 2024
ID http://purl.obolibrary.org/obo/GO_0007268
http://purl.obolibrary.org/obo/GO_0007268
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Preferred name

chemical synaptic transmission

Synonyms

signal transmission across a synapse

Definitions

The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.

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