CL | Classes | AgroPortal

ID	http://purl.obolibrary.org/obo/PR_000030035 http://purl.obolibrary.org/obo/PR_000030035 https://agroportal.lirmm.fr/ontologies/CL/PR_000030035 Loading
Preferred name	G-protein coupled receptor
Synonyms	fam:GPCR 7TM receptor seven-transmembrane receptor
Definitions	Category=family. Classification based on GRAFS system. [PMID:12761335] A protein that has G protein-coupled receptor (GPCR) activity. Each GPCR consists of a single polypeptide with an extracellular N-terminus, an intracellular C-terminus and seven hydrophobic transmembrane domains (TM1-TM7) linked by three extracellular loops (ECL1-ECL3) and three intracellular loops (ICL1-ICL3). GPCRs function as part of a heterotrimeric complex to transmit an extracellular signal across the membrane by activating an associated G-protein via the exchange of GDP for GTP on the alpha subunit.

rdfs:comment	Category=family. Classification based on GRAFS system. [PMID:12761335]
rdf:type	http://www.w3.org/2002/07/owl#Class Loading
rdfs:subClassOf	http://purl.obolibrary.org/obo/BFO_0000004 Loading http://purl.obolibrary.org/obo/BFO_0000040 Loading http://purl.obolibrary.org/obo/PR_000000001 Loading http://purl.obolibrary.org/obo/CHEBI_36080 Loading
rdfs:label	G-protein coupled receptor
skos:notation	PR:000030035
obo_purl:IAO_0000115	A protein that has G protein-coupled receptor (GPCR) activity. Each GPCR consists of a single polypeptide with an extracellular N-terminus, an intracellular C-terminus and seven hydrophobic transmembrane domains (TM1-TM7) linked by three extracellular loops (ECL1-ECL3) and three intracellular loops (ICL1-ICL3). GPCRs function as part of a heterotrimeric complex to transmit an extracellular signal across the membrane by activating an associated G-protein via the exchange of GDP for GTP on the alpha subunit.
oboinowl_gen:hasExactSynonym	fam:GPCR
oboinowl_gen:hasDbXref	IUPHARfam:694
oboinowl_gen:hasOBONamespace	protein
oboinowl_gen:id	PR:000030035
oboinowl_gen:hasBroadSynonym	7TM receptor seven-transmembrane receptor
obo_purl:RO_0002215	http://purl.obolibrary.org/obo/GO_0004930 Loading

Subject	Author	Type	Created
No notes to display