Vertebrate Trait Ontology (VT)
OWL
Last submission date November 16, 2024
ID http://purl.obolibrary.org/obo/VT_0004435
http://purl.obolibrary.org/obo/VT_0004435
https://agroportal.lirmm.fr/ontologies/VT/VT_0004435
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Preferred name

cochlear outer hair cell electromotility trait

Synonyms
electromechanical transduction
OHC electromotility
Definitions
Any measurable or observable characteristic related to the motility of the cochlear OHCs in response to electrical stimulation; normally, the motile response (i.e. rapid change in length and stiffness of OHCs) is closely coupled to the changing transduction current and provides a region-specific amplification in the movement of the spiral organ that enhances transduction at the IHCs in that specific region of the cochlear spiral, increasing both sensitivity and specificity; electromotility is believed to arise through voltage-gated conformational changes in motor protein (prestin) or proteins located in the lateral wall of the OHC.
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