<?xml version="1.0" encoding="UTF-8"?> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:obo_purl="http://purl.obolibrary.org/obo/" xmlns:owl="http://www.w3.org/2002/07/owl#" xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#" xmlns:skos="http://www.w3.org/2004/02/skos/core#" xmlns:oboinowl_gen="http://www.geneontology.org/formats/oboInOwl#" xmlns:metadata_def="http://data.bioontology.org/metadata/def/" xmlns:metadata="http://data.bioontology.org/metadata/"> <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000948"> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0007100"/> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0004120"/> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0005181"/> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0010314"/> <rdfs:label>heart</rdfs:label> <rdfs:comment>Taxon notes:" the ascidian tube-like heart lacks chambers....The ascidian heart is formed after metamorphosis as a simple tube-like structure with a single-layered myoepithelium that is continuous with a single-layered pericar- dial wall. It lacks chambers and endocardium.... The innovation of the chambered heart was a key event in vertebrate evolution, because the chambered heart generates one-way blood flow with high pressure, a critical requirement for the efficient blood supply of large-body vertebrates... all extant vertebrates have hearts with two or more chambers (Moorman and Christoffels 2003)" DOI:10.1101/gad.1485706</rdfs:comment> <skos:notation>UBERON:0000948</skos:notation> <obo_purl:IAO_0000115>A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ.</obo_purl:IAO_0000115> <oboinowl_gen:hasExactSynonym>chambered heart</oboinowl_gen:hasExactSynonym> <oboinowl_gen:hasExactSynonym>vertebrate heart</oboinowl_gen:hasExactSynonym> <oboinowl_gen:hasDbXref>AAO:0010210</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>BILA:0000020</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>BTO:0000562</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>CALOHA:TS-0445</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>EFO:0000815</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>EHDAA2:0000738</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>EHDAA:420</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>EMAPA:16105</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>EV:0100018</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>FMA:7088</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>GAID:174</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>MA:0000072</oboinowl_gen:hasDbXref> 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