@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> . @prefix obo_purl: <http://purl.obolibrary.org/obo/> . @prefix owl: <http://www.w3.org/2002/07/owl#> . @prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> . @prefix skos: <http://www.w3.org/2004/02/skos/core#> . @prefix oboinowl_gen: <http://www.geneontology.org/formats/oboInOwl#> . @prefix ns0: <http://purl.obolibrary.org/obo/go#> . @prefix metadata_def: <http://data.bioontology.org/metadata/def/> . obo_purl:GO_0000133 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0000417 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0000796 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0000808 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0000930 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0000939 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0000940 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0000974 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0001114 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0001534 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0001535 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0001536 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0002096 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0002133 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0002142 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0002167 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0002193 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0002199 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0002929 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0005577 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0005581 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0005602 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0005616 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0005663 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0005667 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0005831 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0005833 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0005838 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0005850 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0005852 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0005853 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0005854 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0005861 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0005862 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0005875 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0005885 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0005931 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0008091 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0008278 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0008290 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0008537 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0008540 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0008541 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0009321 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0009390 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0015627 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0016272 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0016459 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0017102 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0018444 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0019035 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0019036 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0019773 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0019774 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0019814 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0022623 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0022624 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0030076 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0030080 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0030081 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0030082 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0030256 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0030257 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0030314 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0030990 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0030991 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0030992 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0030993 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0031074 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0031105 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0031209 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0031262 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0031389 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0031395 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0031511 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0031521 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0031680 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0031838 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0031941 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0032300 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0032311 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0032766 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0032777 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0032991 metadata_def:mappingLoom "proteincontainingcomplex" ; metadata_def:mappingSameURI obo_purl:GO_0032991 ; metadata_def:prefLabel "protein-containing complex" ; obo_purl:IAO_0000115 "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together." ; oboinowl_gen:hasAlternativeId "GO:0043234" ; oboinowl_gen:hasExactSynonym "macromolecular complex", "macromolecule complex", "protein containing complex" ; oboinowl_gen:hasNarrowSynonym "protein complex", "protein-protein complex" ; oboinowl_gen:hasOBONamespace "cellular_component" ; oboinowl_gen:id "GO:0032991" ; oboinowl_gen:inSubset ns0:goslim_agr, ns0:goslim_chembl, ns0:goslim_euk_cellular_processes_ribbon, ns0:goslim_flybase_ribbon, ns0:goslim_mouse, ns0:goslim_pir ; a owl:Class ; rdfs:comment "A protein complex in this context is meant as a stable set of interacting proteins which can be co-purified by an acceptable method, and where the complex has been shown to exist as an isolated, functional unit in vivo. Acceptable experimental methods include stringent protein purification followed by detection of protein interaction. The following methods should be considered non-acceptable: simple immunoprecipitation, pull-down experiments from cell extracts without further purification, colocalization and 2-hybrid screening. Interactions that should not be captured as protein complexes include: 1) enzyme/substrate, receptor/ligand or any similar transient interactions, unless these are a critical part of the complex assembly or are required e.g. for the receptor to be functional; 2) proteins associated in a pull-down/co-immunoprecipitation assay with no functional link or any evidence that this is a defined biological entity rather than a loose-affinity complex; 3) any complex where the only evidence is based on genetic interaction data; 4) partial complexes, where some subunits (e.g. transmembrane ones) cannot be expressed as recombinant proteins and are excluded from experiments (in this case, independent evidence is necessary to find out the composition of the full complex, if known). Interactions that may be captured as protein complexes include: 1) enzyme/substrate or receptor/ligand if the complex can only assemble and become functional in the presence of both classes of subunits; 2) complexes where one of the members has not been shown to be physically linked to the other(s), but is a homologue of, and has the same functionality as, a protein that has been experimentally demonstrated to form a complex with the other member(s); 3) complexes whose existence is accepted based on localization and pharmacological studies, but for which experimental evidence is not yet available for the complex as a whole." ; rdfs:label "protein-containing complex" ; rdfs:subClassOf obo_purl:GO_0005575 ; skos:notation "GO:0032991" . obo_purl:GO_0032992 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0032993 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0032994 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0033061 rdfs:subClassOf obo_purl:GO_0032991 . obo_purl:GO_0033104 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