<?xml version="1.0" encoding="UTF-8"?> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:obo_purl="http://purl.obolibrary.org/obo/" xmlns:owl="http://www.w3.org/2002/07/owl#" xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#" xmlns:skos="http://www.w3.org/2004/02/skos/core#" xmlns:oboinowl_gen="http://www.geneontology.org/formats/oboInOwl#" xmlns:metadata_def="http://data.bioontology.org/metadata/def/"> <owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0009922"> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0016747"/> <rdfs:label>fatty acid elongase activity</rdfs:label> <skos:notation>GO:0009922</skos:notation> <obo_purl:IAO_0000115>Catalysis of the reaction: a very-long-chain acyl-CoA + H+ + malonyl-CoA = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA. This reaction is the first (condensation) step of the four-step fatty acid elongation cycle in the endoplasmic reticulum that extends fatty acids of C-16 or longer with an additional 2-C unit.</obo_purl:IAO_0000115> <oboinowl_gen:hasExactSynonym>ELOVL</oboinowl_gen:hasExactSynonym> <oboinowl_gen:hasExactSynonym>elongation of very long chain fatty acids activity</oboinowl_gen:hasExactSynonym> <oboinowl_gen:hasExactSynonym>very-long-chain 3-ketoacyl-CoA synthase</oboinowl_gen:hasExactSynonym> <oboinowl_gen:hasExactSynonym>very-long-chain 3-oxoacyl-CoA synthase</oboinowl_gen:hasExactSynonym> <oboinowl_gen:hasExactSynonym>very-long-chain beta-ketoacyl-CoA synthase</oboinowl_gen:hasExactSynonym> <oboinowl_gen:hasDbXref>EC:2.3.1.199</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>MetaCyc:RXN-7697</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>RHEA:32727</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>Reactome:R-HSA-2046083</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>Reactome:R-HSA-2046088</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>Reactome:R-HSA-2046090</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>Reactome:R-HSA-2046094</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>Reactome:R-HSA-2046095</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>Reactome:R-HSA-2046100</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>Reactome:R-HSA-548800</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>Reactome:R-HSA-548814</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>Reactome:R-HSA-548815</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>Reactome:R-HSA-548830</oboinowl_gen:hasDbXref> <oboinowl_gen:hasOBONamespace>molecular_function</oboinowl_gen:hasOBONamespace> <oboinowl_gen:id>GO:0009922</oboinowl_gen:id> <metadata_def:prefLabel>fatty acid elongase activity</metadata_def:prefLabel> <oboinowl_gen:hasBroadSynonym>condensing enzyme</oboinowl_gen:hasBroadSynonym> <metadata_def:mappingLoom>fattyacidelongaseactivity</metadata_def:mappingLoom> <metadata_def:mappingSameURI rdf:resource="http://purl.obolibrary.org/obo/GO_0009922"/> <obo_purl:IAO_0000233 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/geneontology/go-ontology/issues/25805</obo_purl:IAO_0000233> <obo_purl:IAO_0000233 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/geneontology/go-ontology/issues/24752</obo_purl:IAO_0000233> </owl:Class> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0033807"> <oboinowl_gen:consider> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0009922"> <metadata_def:mappingSameURI rdf:resource="http://purl.obolibrary.org/obo/GO_0009922"/> </rdf:Description> </oboinowl_gen:consider> </rdf:Description> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0102336"> <obo_purl:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/GO_0009922"/> </rdf:Description> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0102337"> <obo_purl:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/GO_0009922"/> </rdf:Description> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0102338"> <obo_purl:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/GO_0009922"/> </rdf:Description> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0102756"> <obo_purl:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/GO_0009922"/> </rdf:Description> </rdf:RDF>