{"@context":{"obo_purl":"http://purl.obolibrary.org/obo/","rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","owl":"http://www.w3.org/2002/07/owl#","rdfs":"http://www.w3.org/2000/01/rdf-schema#","oboinowl_gen":"http://www.geneontology.org/formats/oboInOwl#","ns0":"http://purl.obolibrary.org/obo/cl#","ns1":"http://purl.obolibrary.org/obo/uberon/core#","metadata_def":"http://data.bioontology.org/metadata/def/","metadata":"http://data.bioontology.org/metadata/","ns2":"http://data.bioontology.org/metadata/obo/"},"@graph":[{"@id":"obo_purl:CL_0000115","@type":"owl:Class","rdfs:subClassOf":[{"@id":"obo_purl:CL_0000213"},{"@id":"obo_purl:CL_0000255"},{"@id":"obo_purl:BFO_0000002"}],"rdfs:label":"endothelial cell","rdfs:comment":"From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard].","obo_purl:IAO_0000115":"An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm.","oboinowl_gen:hasExactSynonym":"endotheliocyte","oboinowl_gen:hasDbXref":["BTO:0001176","CALOHA:TS-0278","FMA:66772"],"oboinowl_gen:inSubset":[{"@id":"ns0:cellxgene_subset"},{"@id":"ns1:human_reference_atlas"}],"metadata:def/prefLabel":"endothelial cell","metadata:def/mappingLoom":"endothelialcell","metadata:def/mappingSameURI":{"@id":"obo_purl:CL_0000115"},"metadata:prefixIRI":"CL:0000115","metadata:treeView":{"@id":"obo_purl:CL_0000222"},"metadata:obo/develops_from":{"@id":"obo_purl:CL_0000222"}},{"@id":"obo_purl:CL_0000071","rdfs:subClassOf":{"@id":"obo_purl:CL_0000115"}},{"@id":"obo_purl:CL_0000666","rdfs:subClassOf":{"@id":"obo_purl:CL_0000115"}},{"@id":"obo_purl:CL_0002139","rdfs:subClassOf":{"@id":"obo_purl:CL_0000115"}},{"@id":"obo_purl:CL_0002262","rdfs:subClassOf":{"@id":"obo_purl:CL_0000115"}},{"@id":"obo_purl:CL_0002350","rdfs:subClassOf":{"@id":"obo_purl:CL_0000115"}},{"@id":"obo_purl:CL_0002653","rdfs:subClassOf":{"@id":"obo_purl:CL_0000115"}},{"@id":"obo_purl:CL_0010008","rdfs:subClassOf":{"@id":"obo_purl:CL_0000115"}},{"@id":"obo_purl:CL_1000412","rdfs:subClassOf":{"@id":"obo_purl:CL_0000115"}},{"@id":"obo_purl:CL_1000413","rdfs:subClassOf":{"@id":"obo_purl:CL_0000115"}},{"@id":"obo_purl:CL_1001602","rdfs:subClassOf":{"@id":"obo_purl:CL_0000115"}},{"@id":"obo_purl:UBERON_0006965","obo_purl:BFO_0000051":{"@id":"obo_purl:CL_0000115"}},{"@id":"obo_purl:GO_0072577","obo_purl:BFO_0000066":{"@id":"obo_purl:CL_0000115"}},{"@id":"obo_purl:GO_0001885","obo_purl:RO_0002296":{"@id":"obo_purl:CL_0000115"}},{"@id":"obo_purl:GO_0001886","obo_purl:RO_0002298":{"@id":"obo_purl:CL_0000115"}},{"@id":"obo_purl:GO_0045446","obo_purl:RO_0002315":{"@id":"obo_purl:CL_0000115"}},{"@id":"obo_purl:UBERON_0001986","obo_purl:RO_0002473":{"@id":"obo_purl:CL_0000115"}},{"@id":"obo_purl:GO_0043542","obo_purl:RO_0002565":{"@id":"obo_purl:CL_0000115"}},{"@id":"obo_purl:GO_0042118","obo_purl:RO_0004009":{"@id":"obo_purl:CL_0000115"}},{"@id":"obo_purl:GO_0001935","obo_purl:RO_0012003":{"@id":"obo_purl:CL_0000115"}}]}