{"@context":{"obo_purl":"http://purl.obolibrary.org/obo/","rdf":"http://www.w3.org/1999/02/22-rdf-syntax-ns#","owl":"http://www.w3.org/2002/07/owl#","rdfs":"http://www.w3.org/2000/01/rdf-schema#","skos":"http://www.w3.org/2004/02/skos/core#","oboinowl_gen":"http://www.geneontology.org/formats/oboInOwl#","foaf":"http://xmlns.com/foaf/0.1/","ns0":"http://purl.obolibrary.org/obo/uberon/core#","metadata_def":"http://data.bioontology.org/metadata/def/","ns1":"http://data.bioontology.org/rest_backup_mappings/","metadata":"http://data.bioontology.org/metadata/","ns2":"http://data.bioontology.org/metadata/obo/","ns3":"http://www.ebi.ac.uk/efo/"},"@graph":[{"@id":"obo_purl:UBERON_0000948","@type":"owl:Class","rdfs:subClassOf":{"@id":"obo_purl:UBERON_0000061"},"rdfs:label":"heart","rdfs:comment":"Taxon notes:\" the ascidian tube-like heart lacks chambers....The ascidian heart is formed after metamorphosis as a simple tube-like structure with a single-layered myoepithelium that is continuous with a single-layered pericar- dial wall. It lacks chambers and endocardium.... The innovation of the chambered heart was a key event in vertebrate evolution, because the chambered heart generates one-way blood flow with high pressure, a critical requirement for the efficient blood supply of large-body vertebrates... all extant vertebrates have hearts with two or more chambers (Moorman and Christoffels 2003)\" DOI:10.1101/gad.1485706","skos:notation":"UBERON:0000948","obo_purl:IAO_0000115":"A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ.","oboinowl_gen:hasExactSynonym":["chambered heart","vertebrate heart"],"foaf:depiction":[{"@type":"http://www.w3.org/2001/XMLSchema#anyURI","@value":"https://cdn.humanatlas.io/digital-objects/ref-organ/heart-female/v1.3/assets/3d-vh-f-heart.glb"},{"@type":"http://www.w3.org/2001/XMLSchema#anyURI","@value":"https://cdn.humanatlas.io/digital-objects/ref-organ/heart-male/v1.3/assets/3d-vh-m-heart.glb"}],"oboinowl_gen:hasDbXref":["AAO:0010210","BILA:0000020","BTO:0000562","CALOHA:TS-0445","EFO:0000815","EHDAA2:0000738","EHDAA:420","EMAPA:16105","EV:0100018","FMA:7088","GAID:174","MA:0000072","MAT:0000036","MESH:D006321","MIAA:0000036","NCIT:C12727","SCTID:302509004","TAO:0000114","VHOG:0000276","Wikipedia:Heart","XAO:0000064","ZFA:0000114","galen:Heart","UMLS:C0018787"],"oboinowl_gen:hasOBONamespace":"uberon","oboinowl_gen:id":"UBERON:0000948","oboinowl_gen:inSubset":[{"@id":"ns0:human_subset"},{"@id":"ns0:mouse_subset"},{"@id":"ns0:major_organ"},{"@id":"ns0:organ_slim"},{"@id":"ns0:pheno_slim"},{"@id":"ns0:efo_slim"},{"@id":"ns0:human_reference_atlas"},{"@id":"ns0:uberon_slim"},{"@id":"ns0:vertebrate_core"}],"metadata:def/mappingRest":{"@id":"ns1:70ac9170-b28f-0136-7fbc-525400026749"},"metadata:def/prefLabel":"heart","oboinowl_gen:hasNarrowSynonym":"branchial heart","oboinowl_gen:hasRelatedSynonym":"cardium","metadata:def/mappingLoom":"heart","metadata:def/mappingSameURI":{"@id":"obo_purl:UBERON_0000948"},"metadata:treeView":[{"@id":"obo_purl:UBERON_0001009"},{"@id":"obo_purl:UBERON_0015410"},{"@id":"obo_purl:UBERON_0000467"},{"@id":"obo_purl:UBERON_0000915"},{"@id":"obo_purl:UBERON_0002100"}],"metadata:obo/part_of":[{"@id":"obo_purl:UBERON_0001009"},{"@id":"obo_purl:UBERON_0015410"},{"@id":"obo_purl:UBERON_0000467"},{"@id":"obo_purl:UBERON_0000915"},{"@id":"obo_purl:UBERON_0002100"}],"obo_purl:RO_0002161":[{"@id":"obo_purl:NCBITaxon_7227"},{"@id":"obo_purl:NCBITaxon_6239"}],"obo_purl:RO_0002175":{"@id":"obo_purl:NCBITaxon_9606"},"obo_purl:UBPROP_0000001":["Part of the circulatory system responsible for pumping blood; composed of three chambers--two atria and one ventricle.[AAO]","Blood pumping organ composed of four chambers: sinus venosus, atrium, cardiac ventricle and bulbus arteriosus.[TAO]"],"obo_purl:UBPROP_0000002":"relationship type change: differentiates_from lateral plate mesoderm (AAO:0010574) CHANGED TO: develops_from lateral plate mesoderm (UBERON:0003081)[AAO]","obo_purl:UBPROP_0000003":"As noted, the hearts of birds and mammals have four chambers that arises from the two chambers (atrium and ventricle) of the fish heart.[well established][VHOG]","obo_purl:UBPROP_0000007":"cardiac"},{"@id":"ns3:EFO_0005043","obo_purl:IAO_0000136":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"ns3:EFO_0005128","obo_purl:IAO_0000136":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"ns3:EFO_0007928","obo_purl:IAO_0000136":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"ns3:EFO_0008003","obo_purl:IAO_0000136":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"ns3:EFO_0008398","obo_purl:IAO_0000136":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"ns3:EFO_0008468","obo_purl:IAO_0000136":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"ns3:EFO_0008469","obo_purl:IAO_0000136":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"ns3:EFO_0009184","obo_purl:IAO_0000136":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"ns3:EFO_0009185","obo_purl:IAO_0000136":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"ns3:EFO_0009285","obo_purl:IAO_0000136":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"ns3:EFO_0009288","obo_purl:IAO_0000136":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"ns3:EFO_0009289","obo_purl:IAO_0000136":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"ns3:EFO_0009290","obo_purl:IAO_0000136":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"ns3:EFO_0009291","obo_purl:IAO_0000136":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"ns3:EFO_0010071","obo_purl:IAO_0000136":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"ns3:EFO_0010555","obo_purl:IAO_0000136":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"ns3:EFO_0010556","obo_purl:IAO_0000136":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"ns3:EFO_0600009","obo_purl:IAO_0000136":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"ns3:EFO_0600032","obo_purl:IAO_0000136":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"obo_purl:UBERON_0001621","metadata:obo/part_of":{"@id":"obo_purl:UBERON_0000948"},"metadata:treeView":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"ns3:EFO_0001955","metadata:obo/part_of":{"@id":"obo_purl:UBERON_0000948"},"metadata:treeView":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"obo_purl:UBERON_0000946","metadata:obo/part_of":{"@id":"obo_purl:UBERON_0000948"},"metadata:treeView":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"obo_purl:UBERON_0004152","metadata:obo/part_of":{"@id":"obo_purl:UBERON_0000948"},"metadata:treeView":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"obo_purl:UBERON_0005440","metadata:obo/part_of":{"@id":"obo_purl:UBERON_0000948"},"metadata:treeView":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"obo_purl:UBERON_0005983","metadata:obo/part_of":{"@id":"obo_purl:UBERON_0000948"},"metadata:treeView":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"obo_purl:UBERON_0005985","metadata:obo/part_of":{"@id":"obo_purl:UBERON_0000948"},"metadata:treeView":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"obo_purl:UBERON_0037144","metadata:obo/part_of":{"@id":"obo_purl:UBERON_0000948"},"metadata:treeView":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"obo_purl:UBERON_0002078","metadata:obo/part_of":{"@id":"obo_purl:UBERON_0000948"},"metadata:treeView":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"obo_purl:UBERON_0002079","metadata:obo/part_of":{"@id":"obo_purl:UBERON_0000948"},"metadata:treeView":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"obo_purl:UBERON_0002080","metadata:obo/part_of":{"@id":"obo_purl:UBERON_0000948"},"metadata:treeView":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"obo_purl:UBERON_0002081","metadata:obo/part_of":{"@id":"obo_purl:UBERON_0000948"},"metadata:treeView":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"obo_purl:UBERON_0002082","metadata:obo/part_of":{"@id":"obo_purl:UBERON_0000948"},"metadata:treeView":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"obo_purl:UBERON_0002084","metadata:obo/part_of":{"@id":"obo_purl:UBERON_0000948"},"metadata:treeView":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"obo_purl:UBERON_0002094","metadata:obo/part_of":{"@id":"obo_purl:UBERON_0000948"},"metadata:treeView":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"obo_purl:UBERON_0002165","metadata:obo/part_of":{"@id":"obo_purl:UBERON_0000948"},"metadata:treeView":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"obo_purl:UBERON_0002348","metadata:obo/part_of":{"@id":"obo_purl:UBERON_0000948"},"metadata:treeView":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"obo_purl:UBERON_0002349","metadata:obo/part_of":{"@id":"obo_purl:UBERON_0000948"},"metadata:treeView":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"obo_purl:UBERON_0005989","metadata:obo/part_of":{"@id":"obo_purl:UBERON_0000948"},"metadata:treeView":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"obo_purl:OBA_2045275","obo_purl:RO_0000052":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"obo_purl:OBA_VT0000277","obo_purl:RO_0002314":{"@id":"obo_purl:UBERON_0000948"},"obo_purl:RO_0000052":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"ns3:EFO_0002503","obo_purl:RO_0000052":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"ns3:EFO_0003046","obo_purl:BFO_0000066":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"obo_purl:UBERON_0000033","obo_purl:RO_0002171":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"obo_purl:OBA_0006021","obo_purl:RO_0002314":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"obo_purl:OBA_2050102","obo_purl:RO_0002314":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"obo_purl:OBA_VT0004063","obo_purl:RO_0002314":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"obo_purl:MONDO_0001707","obo_purl:RO_0004026":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"ns3:EFO_1001339","obo_purl:RO_0004026":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"ns3:EFO_0001645","obo_purl:RO_0004026":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"ns3:EFO_0000612","obo_purl:RO_0004026":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"ns3:EFO_0003144","obo_purl:RO_0004026":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"ns3:EFO_0005672","obo_purl:RO_0004026":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"ns3:EFO_1001442","obo_purl:RO_0004026":{"@id":"obo_purl:UBERON_0000948"}},{"@id":"ns3:EFO_1001161","obo_purl:RO_0004027":{"@id":"obo_purl:UBERON_0000948"}}]}