<?xml version="1.0" encoding="UTF-8"?> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:obo_purl="http://purl.obolibrary.org/obo/" xmlns:owl="http://www.w3.org/2002/07/owl#" xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#" xmlns:oboinowl_gen="http://www.geneontology.org/formats/oboInOwl#" xmlns:metadata_def="http://data.bioontology.org/metadata/def/" xmlns:metadata="http://data.bioontology.org/metadata/"> <owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000127"> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000125"/> <rdfs:label>astrocyte</rdfs:label> <rdfs:comment>Astrocytes are reportedly CD68-negative, CD121a-positive, CD184-positive, CD192-positive, CRF-positive, EGFR-positive, GFAP-positive, GLUT1-positive, MBP-negative, and NGFR-positive.</rdfs:comment> <obo_purl:IAO_0000115>A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from 'star' cells) are irregularly shaped with many long processes, including those with 'end feet' which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and 'reactive astrocytes' (along with microglia) respond to injury.</obo_purl:IAO_0000115> <oboinowl_gen:hasExactSynonym>astrocytic glia</oboinowl_gen:hasExactSynonym> <oboinowl_gen:hasDbXref>BTO:0000099</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>CALOHA:TS-0060</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>FMA:54537</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>NCIt:C12477</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>NIFSTD:sao1394521419</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>SNOMEDCT:78399007</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>ZFA:0009075</oboinowl_gen:hasDbXref> <oboinowl_gen:inSubset rdf:resource="http://purl.obolibrary.org/obo/cl#human_subset"/> <oboinowl_gen:inSubset rdf:resource="http://purl.obolibrary.org/obo/cl#mouse_subset"/> <oboinowl_gen:inSubset rdf:resource="http://purl.obolibrary.org/obo/cl#cellxgene_subset"/> <oboinowl_gen:inSubset rdf:resource="http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas"/> <metadata_def:prefLabel>astrocyte</metadata_def:prefLabel> <metadata_def:mappingLoom>astrocyte</metadata_def:mappingLoom> <metadata_def:mappingSameURI rdf:resource="http://purl.obolibrary.org/obo/CL_0000127"/> <metadata:prefixIRI>CL:0000127</metadata:prefixIRI> <obo_purl:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/> <obo_purl:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001017"/> </owl:Class> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000644"> <rdfs:subClassOf> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000127"> <metadata_def:mappingSameURI rdf:resource="http://purl.obolibrary.org/obo/CL_0000127"/> </rdf:Description> </rdfs:subClassOf> </rdf:Description> <rdf:Description rdf:about="http://www.ebi.ac.uk/efo/EFO_0000272"> <obo_purl:RO_0004026 rdf:resource="http://purl.obolibrary.org/obo/CL_0000127"/> </rdf:Description> </rdf:RDF>