<?xml version="1.0" encoding="UTF-8"?> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:obo_purl="http://purl.obolibrary.org/obo/" xmlns:owl="http://www.w3.org/2002/07/owl#" xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#" xmlns:oboinowl_gen="http://www.geneontology.org/formats/oboInOwl#" xmlns:dct="http://purl.org/dc/terms/" xmlns:metadata_def="http://data.bioontology.org/metadata/def/" xmlns:metadata="http://data.bioontology.org/metadata/"> <owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000015"> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000586"/> <rdfs:label>male germ cell</rdfs:label> <rdfs:seeAlso>https://github.com/obophenotype/cell-ontology/issues/574</rdfs:seeAlso> <obo_purl:IAO_0000115>A germ cell that supports male gamete production. In some species, non-germ cells known as Sertoli cells also play a role in spermatogenesis.</obo_purl:IAO_0000115> <oboinowl_gen:hasDbXref>FMA:72290</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>MA:0002765</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>VHOG:0001531</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>ncithesaurus:Spermatogenic_Cell</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>https://cellxgene.cziscience.com/cellguide/CL_0000015</oboinowl_gen:hasDbXref> <oboinowl_gen:inSubset rdf:resource="http://purl.obolibrary.org/obo/cl#human_subset"/> <oboinowl_gen:inSubset rdf:resource="http://purl.obolibrary.org/obo/cl#mouse_subset"/> <oboinowl_gen:inSubset rdf:resource="http://purl.obolibrary.org/obo/cl#cellxgene_subset"/> <dct:description>Male germ cells are specialized cells that give rise to the male gametes and are therefore crucial for sexual reproduction in males. Through a complex process called spermatogenesis in the testes male germ cells undergo several stages of development, each with distinctive morphological and physiological characteristics, eventually differentiating into mature spermatozoa (sperm). Male germ cells are responsible for transferring genetic material from male to offspring as part of sexual reproduction. In the initial stage of their life cycle, they exist as spermatogonial stem cells, which multiply by mitotic division to self-renew and to produce daughter cells. The daughter cells then undergo meiotic division, a process that reduces the number of chromosomes in each cell by half, from diploid to haploid – the formation of spermatids. This is critical for maintaining genetic stability from generation to generation, as it ensures that when an egg and sperm cell unite during fertilization, the resulting offspring will have the correct number of chromosomes. The final phase of spermatogenesis is called spermiogenesis, during which spermatozoa - mature and motile sperm cells – are produced from round spermatids. The matured male germ cells or sperm cells are highly specialized, having a streamlined shape designed for efficient movement towards the female egg. A sperm cell is divided into three main parts, namely the head, midpiece, and tail. The head contains the genetic material, the midpiece contains mitochondria that provide energy, and the tail, termed as the flagellum, propels the sperm cell forward. Each of these parts play significant roles in fertilization. (This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)</dct:description> <metadata_def:prefLabel>male germ cell</metadata_def:prefLabel> <metadata_def:mappingLoom>malegermcell</metadata_def:mappingLoom> <metadata_def:mappingSameURI rdf:resource="http://purl.obolibrary.org/obo/CL_0000015"/> <metadata:prefixIRI>CL:0000015</metadata:prefixIRI> </owl:Class> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000019"> <rdfs:subClassOf> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000015"> <metadata_def:mappingSameURI rdf:resource="http://purl.obolibrary.org/obo/CL_0000015"/> </rdf:Description> </rdfs:subClassOf> </rdf:Description> </rdf:RDF>