<?xml version="1.0" encoding="UTF-8"?> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:obo_purl="http://purl.obolibrary.org/obo/" xmlns:owl="http://www.w3.org/2002/07/owl#" xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#" xmlns:skos="http://www.w3.org/2004/02/skos/core#" xmlns:oboinowl_gen="http://www.geneontology.org/formats/oboInOwl#" xmlns:metadata_def="http://data.bioontology.org/metadata/def/"> <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_50750"> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23924"/> <rdfs:label>EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor</rdfs:label> <skos:notation>CHEBI:50750</skos:notation> <obo_purl:IAO_0000115>A topoisomerase inhibitor that inhibits DNA topoisomerase (ATP-hydrolysing), EC 5.99.1.3 (also known as topoisomerase II and as DNA gyrase), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands.</obo_purl:IAO_0000115> <oboinowl_gen:hasOBONamespace>chebi_ontology</oboinowl_gen:hasOBONamespace> <oboinowl_gen:id>CHEBI:50750</oboinowl_gen:id> <oboinowl_gen:inSubset rdf:resource="http://purl.obolibrary.org/obo/chebi#3_STAR"/> <metadata_def:prefLabel>EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor</metadata_def:prefLabel> <oboinowl_gen:hasRelatedSynonym>EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitors</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>EC 5.99.1.3 (DNA topoisomerase (ATP-hydrolysing)) inhibitors</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>DNA gyrase inhibitor</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>DNA gyrase inhibitors</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>DNA topoisomerase (ATP-hydrolysing) inhibitor</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>DNA topoisomerase (ATP-hydrolysing) inhibitors</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>DNA topoisomerase II inhibitor</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>DNA topoisomerase II inhibitors</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>EC 5.99.1.3 inhibitor</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>EC 5.99.1.3 inhibitors</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>DNA topoisomerase (ATP-hydrolysing) (EC 5.99.1.3) inhibitors</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>inhibitor of type II topoisomerase</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>inhibitors of type II topoisomerase</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>DNA topoisomerase (ATP-hydrolysing) (EC 5.99.1.3) inhibitor</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>topoisomerase II inhibitor</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>topoisomerase II inhibitors</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>topoisomerase-II inhibitor</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>topoisomerase-II inhibitors</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>type II DNA topoisomerase inhibitor</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>type II DNA topoisomerase inhibitors</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>EC 5.99.1.3 (DNA topoisomerase (ATP-hydrolysing)) inhibitor</oboinowl_gen:hasRelatedSynonym> <metadata_def:mappingLoom>ec59913dnatopoisomeraseatphydrolysinginhibitor</metadata_def:mappingLoom> <metadata_def:mappingSameURI rdf:resource="http://purl.obolibrary.org/obo/CHEBI_50750"/> <oboinowl_gen:hasAlternativeId>CHEBI:132229</oboinowl_gen:hasAlternativeId> <oboinowl_gen:hasAlternativeId>CHEBI:50234</oboinowl_gen:hasAlternativeId> </owl:Class> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_50750"> <metadata_def:mappingSameURI rdf:resource="http://purl.obolibrary.org/obo/CHEBI_50750"/> </rdf:Description> </rdf:RDF>