<?xml version="1.0" encoding="UTF-8"?> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:obo_purl="http://purl.obolibrary.org/obo/" xmlns:owl="http://www.w3.org/2002/07/owl#" xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#" xmlns:skos="http://www.w3.org/2004/02/skos/core#" xmlns:oboinowl_gen="http://www.geneontology.org/formats/oboInOwl#" xmlns:metadata_def="http://data.bioontology.org/metadata/def/"> <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35705"> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23888"/> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_24432"/> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_51086"/> <rdfs:label>immunosuppressive agent</rdfs:label> <skos:notation>CHEBI:35705</skos:notation> <obo_purl:IAO_0000115>An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.</obo_purl:IAO_0000115> <oboinowl_gen:hasDbXref>NCIt:C574</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>SNOMEDCT:372823004</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>SNOMEDCT:69431002</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>MESH:D007166</oboinowl_gen:hasDbXref> <oboinowl_gen:hasOBONamespace>chebi_ontology</oboinowl_gen:hasOBONamespace> <oboinowl_gen:id>CHEBI:35705</oboinowl_gen:id> <oboinowl_gen:inSubset rdf:resource="http://purl.obolibrary.org/obo/chebi#3_STAR"/> <metadata_def:prefLabel>immunosuppressive agent</metadata_def:prefLabel> <oboinowl_gen:hasRelatedSynonym>immunosuppressant</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>immunosuppressive agents</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>inmunosupresor</oboinowl_gen:hasRelatedSynonym> <metadata_def:mappingLoom>immunosuppressiveagent</metadata_def:mappingLoom> <metadata_def:mappingSameURI rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35705"/> <obo_purl:RO_0000052 rdf:resource="http://purl.obolibrary.org/obo/CHEBI_24431"/> </owl:Class> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_46345"> <ns2:has_role> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_35705"> <metadata_def:mappingSameURI rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35705"/> </rdf:Description> </ns2:has_role> </rdf:Description> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_50223"> <ns2:has_role rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35705"/> </rdf:Description> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_63599"> <ns2:has_role rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35705"/> </rdf:Description> <rdf:Description rdf:about="http://www.ebi.ac.uk/efo/EFO_0008458"> <obo_purl:IAO_0000136 rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35705"/> </rdf:Description> </rdf:RDF>