@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix obo_purl: <http://purl.obolibrary.org/obo/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix metadata_def: <http://data.bioontology.org/metadata/def/> .
@prefix oboinowl_gen: <http://www.geneontology.org/formats/oboInOwl#> .
@prefix ns0: <http://purl.obolibrary.org/obo/chebi#> .
@prefix ns1: <http://purl.obolibrary.org/obo/chebi/> .
@prefix ns2: <InChI=1S/C7H8ClN3O4S2/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5/> .
obo_purl:CHEBI_5778
metadata_def:mappingLoom "hydrochlorothiazide" ;
metadata_def:mappingSameURI obo_purl:CHEBI_5778 ;
metadata_def:prefLabel "hydrochlorothiazide" ;
obo_purl:IAO_0000115 "A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure." ;
obo_purl:RO_0000087 obo_purl:CHEBI_35498, obo_purl:CHEBI_35674, obo_purl:CHEBI_35703, obo_purl:CHEBI_78298 ;
ns1:charge "0" ;
ns1:formula "C7H8ClN3O4S2" ;
ns1:inchi "InChI=1S/C7H8ClN3O4S2/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5/h1-2,10-11H,3H2,(H2,9,12,13)" ;
ns1:inchikey "JZUFKLXOESDKRF-UHFFFAOYSA-N" ;
ns1:mass "297.73900" ;
ns1:monoisotopicmass "296.96448" ;
ns1:smiles "NS(=O)(=O)c1cc2c(NCNS2(=O)=O)cc1Cl" ;
oboinowl_gen:hasDbXref "CAS:58-93-5", "DrugBank:DB00999", "Drug_Central:1385", "HMDB:HMDB0001928", "KEGG:C07041", "KEGG:D00340", "LINCS:LSM-5308", "PDBeChem:HCZ", "PMID:24055851", "PMID:24657333", "PMID:24849193", "Reaxys:625101", "Wikipedia:Hydrochlorothiazide" ;
oboinowl_gen:hasExactSynonym "6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide" ;
oboinowl_gen:hasOBONamespace "chebi_ontology" ;
oboinowl_gen:hasRelatedSynonym "Esidrix (TN)", "hidroclorotiazida", "hydrochlorothiazide", "hydrochlorothiazidum" ;
oboinowl_gen:id "CHEBI:5778" ;
oboinowl_gen:inSubset <http://purl.obolibrary.org/obo/chebi#3_STAR> ;
a owl:Class ;
rdfs:label "hydrochlorothiazide" ;
rdfs:subClassOf obo_purl:CHEBI_35358, obo_purl:CHEBI_36683, obo_purl:CHEBI_50265 ;
skos:notation "CHEBI:5778" .
obo_purl:ECTO_9000741
obo_purl:RO_0002309 obo_purl:CHEBI_5778 .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix obo_purl: <http://purl.obolibrary.org/obo/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix metadata_def: <http://data.bioontology.org/metadata/def/> .
@prefix oboinowl_gen: <http://www.geneontology.org/formats/oboInOwl#> .
@prefix ns0: <http://purl.obolibrary.org/obo/chebi#> .
@prefix ns1: <http://purl.obolibrary.org/obo/chebi/> .
@prefix ns2: <InChI=1S/C7H8ClN3O4S2/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5/> .
obo_purl:CHEBI_5778
metadata_def:mappingLoom "hydrochlorothiazide" ;
metadata_def:mappingSameURI obo_purl:CHEBI_5778 ;
metadata_def:prefLabel "hydrochlorothiazide" ;
obo_purl:IAO_0000115 "A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure." ;
obo_purl:RO_0000087 obo_purl:CHEBI_35498, obo_purl:CHEBI_35674, obo_purl:CHEBI_35703, obo_purl:CHEBI_78298 ;
ns1:charge "0" ;
ns1:formula "C7H8ClN3O4S2" ;
ns1:inchi "InChI=1S/C7H8ClN3O4S2/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5/h1-2,10-11H,3H2,(H2,9,12,13)" ;
ns1:inchikey "JZUFKLXOESDKRF-UHFFFAOYSA-N" ;
ns1:mass "297.73900" ;
ns1:monoisotopicmass "296.96448" ;
ns1:smiles "NS(=O)(=O)c1cc2c(NCNS2(=O)=O)cc1Cl" ;
oboinowl_gen:hasDbXref "CAS:58-93-5", "DrugBank:DB00999", "Drug_Central:1385", "HMDB:HMDB0001928", "KEGG:C07041", "KEGG:D00340", "LINCS:LSM-5308", "PDBeChem:HCZ", "PMID:24055851", "PMID:24657333", "PMID:24849193", "Reaxys:625101", "Wikipedia:Hydrochlorothiazide" ;
oboinowl_gen:hasExactSynonym "6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide" ;
oboinowl_gen:hasOBONamespace "chebi_ontology" ;
oboinowl_gen:hasRelatedSynonym "Esidrix (TN)", "hidroclorotiazida", "hydrochlorothiazide", "hydrochlorothiazidum" ;
oboinowl_gen:id "CHEBI:5778" ;
oboinowl_gen:inSubset <http://purl.obolibrary.org/obo/chebi#3_STAR> ;
a owl:Class ;
rdfs:label "hydrochlorothiazide" ;
rdfs:subClassOf obo_purl:CHEBI_35358, obo_purl:CHEBI_36683, obo_purl:CHEBI_50265 ;
skos:notation "CHEBI:5778" .
obo_purl:ECTO_9000741
obo_purl:RO_0002309 obo_purl:CHEBI_5778 .