@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix obo_purl: <http://purl.obolibrary.org/obo/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix metadata_def: <http://data.bioontology.org/metadata/def/> .
@prefix oboinowl_gen: <http://www.geneontology.org/formats/oboInOwl#> .
@prefix ns0: <http://purl.obolibrary.org/obo/chebi#> .
@prefix ns1: <http://purl.obolibrary.org/obo/chebi/> .
@prefix ns2: <InChI=1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/> .
obo_purl:CHEBI_49603
metadata_def:mappingLoom "lapatinib" ;
metadata_def:mappingSameURI obo_purl:CHEBI_49603 ;
metadata_def:prefLabel "lapatinib" ;
obo_purl:RO_0000087 obo_purl:CHEBI_35610, obo_purl:CHEBI_38637 ;
ns0:has_functional_parent obo_purl:CHEBI_5115 ;
ns1:charge "0" ;
ns1:formula "C29H26ClFN4O4S" ;
ns1:inchi "InChI=1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35)" ;
ns1:inchikey "BCFGMOOMADDAQU-UHFFFAOYSA-N" ;
ns1:mass "581.05840" ;
ns1:monoisotopicmass "580.13473" ;
ns1:smiles "CS(=O)(=O)CCNCc1ccc(o1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1" ;
oboinowl_gen:hasAlternativeId "CHEBI:38636", "CHEBI:49602" ;
oboinowl_gen:hasDbXref "Beilstein:10502247", "CAS:231277-92-2", "DrugBank:DB01259", "Drug_Central:1548", "LINCS:LSM-1051", "PDBeChem:FMM", "Wikipedia:Lapatinib" ;
oboinowl_gen:hasExactSynonym "N-[3-chloro-4-(3-fluorobenzyloxy)phenyl]-6-[5-({[2-(methanesulfonyl)ethyl]amino}methyl)furan-2-yl]quinazolin-4-amine" ;
oboinowl_gen:hasOBONamespace "chebi_ontology" ;
oboinowl_gen:hasRelatedSynonym "GW 572016", "N-(3-chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine", "N-{3-CHLORO-4-[(3-FLUOROBENZYL)OXY]PHENYL}-6-[5-({[2-(METHYLSULFONYL)ETHYL]AMINO}METHYL)-2-FURYL]-4-QUINAZOLINAMINE", "Tykerb" ;
oboinowl_gen:id "CHEBI:49603" ;
oboinowl_gen:inSubset <http://purl.obolibrary.org/obo/chebi#3_STAR> ;
a owl:Class ;
rdfs:label "lapatinib" ;
rdfs:subClassOf obo_purl:CHEBI_24129, obo_purl:CHEBI_36683, obo_purl:CHEBI_37143, obo_purl:CHEBI_38530 ;
skos:notation "CHEBI:49603" .
obo_purl:ECTO_9000260
obo_purl:RO_0002309 obo_purl:CHEBI_49603 .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix obo_purl: <http://purl.obolibrary.org/obo/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix metadata_def: <http://data.bioontology.org/metadata/def/> .
@prefix oboinowl_gen: <http://www.geneontology.org/formats/oboInOwl#> .
@prefix ns0: <http://purl.obolibrary.org/obo/chebi#> .
@prefix ns1: <http://purl.obolibrary.org/obo/chebi/> .
@prefix ns2: <InChI=1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/> .
obo_purl:CHEBI_49603
metadata_def:mappingLoom "lapatinib" ;
metadata_def:mappingSameURI obo_purl:CHEBI_49603 ;
metadata_def:prefLabel "lapatinib" ;
obo_purl:RO_0000087 obo_purl:CHEBI_35610, obo_purl:CHEBI_38637 ;
ns0:has_functional_parent obo_purl:CHEBI_5115 ;
ns1:charge "0" ;
ns1:formula "C29H26ClFN4O4S" ;
ns1:inchi "InChI=1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35)" ;
ns1:inchikey "BCFGMOOMADDAQU-UHFFFAOYSA-N" ;
ns1:mass "581.05840" ;
ns1:monoisotopicmass "580.13473" ;
ns1:smiles "CS(=O)(=O)CCNCc1ccc(o1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1" ;
oboinowl_gen:hasAlternativeId "CHEBI:38636", "CHEBI:49602" ;
oboinowl_gen:hasDbXref "Beilstein:10502247", "CAS:231277-92-2", "DrugBank:DB01259", "Drug_Central:1548", "LINCS:LSM-1051", "PDBeChem:FMM", "Wikipedia:Lapatinib" ;
oboinowl_gen:hasExactSynonym "N-[3-chloro-4-(3-fluorobenzyloxy)phenyl]-6-[5-({[2-(methanesulfonyl)ethyl]amino}methyl)furan-2-yl]quinazolin-4-amine" ;
oboinowl_gen:hasOBONamespace "chebi_ontology" ;
oboinowl_gen:hasRelatedSynonym "GW 572016", "N-(3-chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine", "N-{3-CHLORO-4-[(3-FLUOROBENZYL)OXY]PHENYL}-6-[5-({[2-(METHYLSULFONYL)ETHYL]AMINO}METHYL)-2-FURYL]-4-QUINAZOLINAMINE", "Tykerb" ;
oboinowl_gen:id "CHEBI:49603" ;
oboinowl_gen:inSubset <http://purl.obolibrary.org/obo/chebi#3_STAR> ;
a owl:Class ;
rdfs:label "lapatinib" ;
rdfs:subClassOf obo_purl:CHEBI_24129, obo_purl:CHEBI_36683, obo_purl:CHEBI_37143, obo_purl:CHEBI_38530 ;
skos:notation "CHEBI:49603" .
obo_purl:ECTO_9000260
obo_purl:RO_0002309 obo_purl:CHEBI_49603 .