<?xml version="1.0" encoding="UTF-8"?> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:obo_purl="http://purl.obolibrary.org/obo/" xmlns:owl="http://www.w3.org/2002/07/owl#" xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#" xmlns:skos="http://www.w3.org/2004/02/skos/core#" xmlns:oboinowl_gen="http://www.geneontology.org/formats/oboInOwl#" xmlns:metadata_def="http://data.bioontology.org/metadata/def/"> <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_47426"> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_24129"/> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23134"/> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35358"/> <rdfs:label>furosemide</rdfs:label> <skos:notation>CHEBI:47426</skos:notation> <obo_purl:IAO_0000115>A chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure.</obo_purl:IAO_0000115> <oboinowl_gen:hasExactSynonym>4-chloro-2-{[(furan-2-yl)methyl]amino}-5-sulfamoylbenzoic acid</oboinowl_gen:hasExactSynonym> <oboinowl_gen:hasExactSynonym>Furosemide</oboinowl_gen:hasExactSynonym> <oboinowl_gen:hasDbXref>CAS:54-31-9</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>DrugBank:DB00695</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>Drug_Central:1258</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>HMDB:HMDB0001933</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>KEGG:D00331</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>LINCS:LSM-5847</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>PMID:15286542</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>PMID:18701232</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>Reaxys:1399731</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>VSDB:1770</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>Wikipedia:Furosemide</oboinowl_gen:hasDbXref> <oboinowl_gen:hasOBONamespace>chebi_ontology</oboinowl_gen:hasOBONamespace> <oboinowl_gen:id>CHEBI:47426</oboinowl_gen:id> <oboinowl_gen:inSubset rdf:resource="http://purl.obolibrary.org/obo/chebi#3_STAR"/> <metadata_def:prefLabel>furosemide</metadata_def:prefLabel> <oboinowl_gen:hasRelatedSynonym>4-Chloro-N-(2-furylmethyl)-5-sulfamoylanthranilic acid</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>2-Furfurylamino-4-chloro-5-sulfamoylbenzoic acid</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>4-Chloro-5-sulfamoyl-N-furfuryl-anthranilic acid</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>4-Chloro-N-furfuryl-5-sulfamoylanthranilic acid</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>Frusemide</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>Lasix (TN)</oboinowl_gen:hasRelatedSynonym> <metadata_def:mappingLoom>furosemide</metadata_def:mappingLoom> <metadata_def:mappingSameURI rdf:resource="http://purl.obolibrary.org/obo/CHEBI_47426"/> <oboinowl_gen:hasAlternativeId>CHEBI:47425</oboinowl_gen:hasAlternativeId> <oboinowl_gen:hasAlternativeId>CHEBI:5198</oboinowl_gen:hasAlternativeId> <obo_purl:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35703"/> <obo_purl:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/CHEBI_77608"/> <obo_purl:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/CHEBI_78298"/> <obo_purl:chebi/charge>0</obo_purl:chebi/charge> <obo_purl:chebi/formula>C12H11ClN2O5S</obo_purl:chebi/formula> <obo_purl:chebi/inchi>InChI=1S/C12H11ClN2O5S/c13-9-5-10(15-6-7-2-1-3-20-7)8(12(16)17)4-11(9)21(14,18)19/h1-5,15H,6H2,(H,16,17)(H2,14,18,19)</obo_purl:chebi/inchi> <obo_purl:chebi/inchikey>ZZUFCTLCJUWOSV-UHFFFAOYSA-N</obo_purl:chebi/inchikey> <obo_purl:chebi/mass>330.74400</obo_purl:chebi/mass> <obo_purl:chebi/monoisotopicmass>330.00772</obo_purl:chebi/monoisotopicmass> <obo_purl:chebi/smiles>NS(=O)(=O)c1cc(C(O)=O)c(NCc2ccco2)cc1Cl</obo_purl:chebi/smiles> </owl:Class> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/ECTO_9000716"> <obo_purl:RO_0002309> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_47426"> <metadata_def:mappingSameURI rdf:resource="http://purl.obolibrary.org/obo/CHEBI_47426"/> </rdf:Description> </obo_purl:RO_0002309> </rdf:Description> </rdf:RDF>