<?xml version="1.0" encoding="UTF-8"?> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:obo_purl="http://purl.obolibrary.org/obo/" xmlns:owl="http://www.w3.org/2002/07/owl#" xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#" xmlns:skos="http://www.w3.org/2004/02/skos/core#" xmlns:oboinowl_gen="http://www.geneontology.org/formats/oboInOwl#" xmlns:metadata_def="http://data.bioontology.org/metadata/def/"> <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_23066"> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_38311"/> <rdfs:label>cephalosporin</rdfs:label> <skos:notation>CHEBI:23066</skos:notation> <obo_purl:IAO_0000115>A class of beta-lactam antibiotics differing from the penicillins in having a 6-membered, rather than a 5-membered, side ring. Although cephalosporins are among the most commonly used antibiotics in the treatment of routine infections, and their use is increasing over time, they can cause a range of hypersensitivity reactions, from mild, delayed-onset cutaneous reactions to life-threatening anaphylaxis in patients with immunoglobulin E (IgE)-mediated allergy.</obo_purl:IAO_0000115> <oboinowl_gen:hasExactSynonym>Cephalosporin</oboinowl_gen:hasExactSynonym> <oboinowl_gen:hasDbXref>KEGG:C00875</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>PMID:10069359</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>PMID:11936371</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>PMID:12833570</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>PMID:24269048</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>PMID:3320614</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>PMID:6762896</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>PMID:8426246</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>Wikipedia:Cephalosporin</oboinowl_gen:hasDbXref> <oboinowl_gen:hasOBONamespace>chebi_ontology</oboinowl_gen:hasOBONamespace> <oboinowl_gen:id>CHEBI:23066</oboinowl_gen:id> <oboinowl_gen:inSubset rdf:resource="http://purl.obolibrary.org/obo/chebi#3_STAR"/> <metadata_def:prefLabel>cephalosporin</metadata_def:prefLabel> <oboinowl_gen:hasRelatedSynonym>cephalosphorin</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>cephalosphorins</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>cephalosporins</oboinowl_gen:hasRelatedSynonym> <metadata_def:mappingLoom>cephalosporin</metadata_def:mappingLoom> <metadata_def:mappingSameURI rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23066"/> <oboinowl_gen:hasAlternativeId>CHEBI:3538</oboinowl_gen:hasAlternativeId> <obo_purl:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/CHEBI_88188"/> <obo_purl:chebi/charge>0</obo_purl:chebi/charge> <obo_purl:chebi/formula>C7H5NO3SR2</obo_purl:chebi/formula> <obo_purl:chebi/mass>183.18500</obo_purl:chebi/mass> <obo_purl:chebi/monoisotopicmass>182.99901</obo_purl:chebi/monoisotopicmass> <obo_purl:chebi/smiles>[H][C@]12SCC([*])=C(N1C(=O)[C@H]2[*])C(O)=O</obo_purl:chebi/smiles> </owl:Class> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_29007"> <rdfs:subClassOf> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_23066"> <metadata_def:mappingSameURI rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23066"/> </rdf:Description> </rdfs:subClassOf> </rdf:Description> </rdf:RDF>