<?xml version="1.0" encoding="UTF-8"?> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:obo_purl="http://purl.obolibrary.org/obo/" xmlns:owl="http://www.w3.org/2002/07/owl#" xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#" xmlns:skos="http://www.w3.org/2004/02/skos/core#" xmlns:oboinowl_gen="http://www.geneontology.org/formats/oboInOwl#" xmlns:ns0="http://purl.obolibrary.org/obo/chebi#" xmlns:metadata_def="http://data.bioontology.org/metadata/def/"> <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_17650"> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_24261"/> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_47909"/> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_138141"/> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_139590"/> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_139592"/> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35344"/> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35346"/> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_36885"/> <rdfs:label>cortisol</rdfs:label> <skos:notation>CHEBI:17650</skos:notation> <obo_purl:IAO_0000115>A 17alpha-hydroxy-C21-steroid that is pregn-4-ene substituted by oxo groups at positions 3 and 20 and hydroxy groups at positions 11, 17 and 21. Cortisol is a corticosteroid hormone or glucocorticoid produced by zona fasciculata of the adrenal cortex, which is a part of the adrenal gland. It is usually referred to as the "stress hormone" as it is involved in response to stress and anxiety, controlled by corticotropin-releasing hormone (CRH). It increases blood pressure and blood sugar, and reduces immune responses</obo_purl:IAO_0000115> <oboinowl_gen:hasExactSynonym>cortisol</oboinowl_gen:hasExactSynonym> <oboinowl_gen:hasExactSynonym>11beta,17,21-trihydroxypregn-4-ene-3,20-dione</oboinowl_gen:hasExactSynonym> <oboinowl_gen:hasExactSynonym>Cortisol</oboinowl_gen:hasExactSynonym> <oboinowl_gen:hasDbXref>Beilstein:1354819</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>CAS:50-23-7</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>DrugBank:DB00741</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>Drug_Central:1388</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>KEGG:C00735</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>KEGG:D00088</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>LINCS:LSM-5980</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>LIPID_MAPS_instance:LMST02030001</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>PDBeChem:HCY</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>PMID:10438974</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>PMID:2268561</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>Patent:US2602769</oboinowl_gen:hasDbXref> <oboinowl_gen:hasDbXref>Wikipedia:Hydrocortisone</oboinowl_gen:hasDbXref> <oboinowl_gen:hasOBONamespace>chebi_ontology</oboinowl_gen:hasOBONamespace> <oboinowl_gen:id>CHEBI:17650</oboinowl_gen:id> <oboinowl_gen:inSubset rdf:resource="http://purl.obolibrary.org/obo/chebi#3_STAR"/> <ns0:has_parent_hydride rdf:resource="http://purl.obolibrary.org/obo/CHEBI_8386"/> <metadata_def:prefLabel>cortisol</metadata_def:prefLabel> <oboinowl_gen:hasRelatedSynonym>(11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>11beta,17alpha,21-trihydroxy-4-pregnene-3,20-dione</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>11beta-hydrocortisone</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>17-hydroxycorticosterone</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>4-pregnen-11beta,17alpha,21-triol-3,20-dione</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>Hydrocortisone</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>Kendall's compound F</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>Reichstein's substance M</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>hidrocortisona</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>hydrocortisone</oboinowl_gen:hasRelatedSynonym> <oboinowl_gen:hasRelatedSynonym>hydrocortisonum</oboinowl_gen:hasRelatedSynonym> <metadata_def:mappingLoom>cortisol</metadata_def:mappingLoom> <metadata_def:mappingSameURI rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17650"/> <oboinowl_gen:hasAlternativeId>CHEBI:14023</oboinowl_gen:hasAlternativeId> <oboinowl_gen:hasAlternativeId>CHEBI:24633</oboinowl_gen:hasAlternativeId> <oboinowl_gen:hasAlternativeId>CHEBI:3893</oboinowl_gen:hasAlternativeId> <oboinowl_gen:hasAlternativeId>CHEBI:58221</oboinowl_gen:hasAlternativeId> <obo_purl:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/CHEBI_88188"/> <obo_purl:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35472"/> <obo_purl:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/CHEBI_49167"/> <obo_purl:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/CHEBI_50857"/> <obo_purl:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/CHEBI_75771"/> <obo_purl:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/CHEBI_77746"/> <obo_purl:chebi/charge>0</obo_purl:chebi/charge> <obo_purl:chebi/formula>C21H30O5</obo_purl:chebi/formula> <obo_purl:chebi/inchi>InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1</obo_purl:chebi/inchi> <obo_purl:chebi/inchikey>JYGXADMDTFJGBT-VWUMJDOOSA-N</obo_purl:chebi/inchikey> <obo_purl:chebi/mass>362.45990</obo_purl:chebi/mass> <obo_purl:chebi/monoisotopicmass>362.20932</obo_purl:chebi/monoisotopicmass> <obo_purl:chebi/smiles>[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]1(C)[C@@]2([H])CC[C@]1(O)C(=O)CO</obo_purl:chebi/smiles> </owl:Class> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/ECTO_9000297"> <obo_purl:RO_0002309> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_17650"> <metadata_def:mappingSameURI rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17650"/> </rdf:Description> </obo_purl:RO_0002309> </rdf:Description> </rdf:RDF>