<?xml version="1.0" encoding="UTF-8"?> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:obo_purl="http://purl.obolibrary.org/obo/" xmlns:owl="http://www.w3.org/2002/07/owl#" xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#" xmlns:skos="http://www.w3.org/2004/02/skos/core#" xmlns:oboinowl_gen="http://www.geneontology.org/formats/oboInOwl#" xmlns:metadata_def="http://data.bioontology.org/metadata/def/"> <owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_1904602"> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0098878"/> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0034703"/> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0098665"/> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032991"/> <rdfs:label>serotonin-activated cation-selective channel complex</rdfs:label> <rdfs:comment>An example of this is HTR3A in human (P46098) in PMID:16116092 (inferred from direct assay).</rdfs:comment> <skos:notation>GO:1904602</skos:notation> <obo_purl:IAO_0000115>A protein complex which is capable of serotonin-activated cation-selective channel activity. Mainly found in pre- and postsynaptic membranes of the brain and gastrointestinal tract. Depending on its location it transports Ca2+, Mg2+, Na+ or K+. It is always a pentamer, containing at least the 5HT3A subunit forming 5HT3A homopentamers or 5HT3A/B heteropentamers. In human, 5HT3A/C, A/D and A/E heteropentamers also exist.</obo_purl:IAO_0000115> <oboinowl_gen:hasExactSynonym>5-HT-3 receptor complex</oboinowl_gen:hasExactSynonym> <oboinowl_gen:hasExactSynonym>5-HT3 receptor complex</oboinowl_gen:hasExactSynonym> <oboinowl_gen:hasExactSynonym>5-hydroxytryptamine receptor 3 complex</oboinowl_gen:hasExactSynonym> <oboinowl_gen:hasExactSynonym>5HT3 receptor complex</oboinowl_gen:hasExactSynonym> <oboinowl_gen:creation_date>2015-08-26T13:19:49Z</oboinowl_gen:creation_date> <oboinowl_gen:hasOBONamespace>cellular_component</oboinowl_gen:hasOBONamespace> <oboinowl_gen:id>GO:1904602</oboinowl_gen:id> <metadata_def:prefLabel>serotonin-activated cation-selective channel complex</metadata_def:prefLabel> <oboinowl_gen:hasBroadSynonym>serotonin receptor complex</oboinowl_gen:hasBroadSynonym> <metadata_def:mappingLoom>serotoninactivatedcationselectivechannelcomplex</metadata_def:mappingLoom> <metadata_def:mappingSameURI rdf:resource="http://purl.obolibrary.org/obo/GO_1904602"/> <obo_purl:IAO_0000233 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/geneontology/go-ontology/issues/12942</obo_purl:IAO_0000233> <obo_purl:RO_0002215 rdf:resource="http://purl.obolibrary.org/obo/GO_0022850"/> <obo_purl:RO_0002216 rdf:resource="http://purl.obolibrary.org/obo/GO_0007210"/> </owl:Class> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_1904602"> <metadata_def:mappingSameURI rdf:resource="http://purl.obolibrary.org/obo/GO_1904602"/> </rdf:Description> </rdf:RDF>