<?xml version="1.0" encoding="UTF-8"?> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:obo_purl="http://purl.obolibrary.org/obo/" xmlns:owl="http://www.w3.org/2002/07/owl#" xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#" xmlns:skos="http://www.w3.org/2004/02/skos/core#" xmlns:oboinowl_gen="http://www.geneontology.org/formats/oboInOwl#" xmlns:metadata_def="http://data.bioontology.org/metadata/def/"> <owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0002460"> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0002250"/> <rdfs:label>adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains</rdfs:label> <skos:notation>GO:0002460</skos:notation> <obo_purl:IAO_0000115>An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus.</obo_purl:IAO_0000115> <oboinowl_gen:hasOBONamespace>biological_process</oboinowl_gen:hasOBONamespace> <oboinowl_gen:id>GO:0002460</oboinowl_gen:id> <metadata_def:prefLabel>adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains</metadata_def:prefLabel> <metadata_def:mappingLoom>adaptiveimmuneresponsebasedonsomaticrecombinationofimmunereceptorsbuiltfromimmunoglobulinsuperfamilydomains</metadata_def:mappingLoom> <metadata_def:mappingSameURI rdf:resource="http://purl.obolibrary.org/obo/GO_0002460"/> </owl:Class> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0002456"> <rdfs:subClassOf> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0002460"> <metadata_def:mappingSameURI rdf:resource="http://purl.obolibrary.org/obo/GO_0002460"/> </rdf:Description> </rdfs:subClassOf> </rdf:Description> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0002461"> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0002460"/> </rdf:Description> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0002467"> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0002460"/> </rdf:Description> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0002822"> <obo_purl:RO_0002211 rdf:resource="http://purl.obolibrary.org/obo/GO_0002460"/> </rdf:Description> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0002823"> <obo_purl:RO_0002212 rdf:resource="http://purl.obolibrary.org/obo/GO_0002460"/> </rdf:Description> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0002824"> <obo_purl:RO_0002213 rdf:resource="http://purl.obolibrary.org/obo/GO_0002460"/> </rdf:Description> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0019724"> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0002460"/> </rdf:Description> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0042088"> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0002460"/> </rdf:Description> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0072538"> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0002460"/> </rdf:Description> </rdf:RDF>