<?xml version="1.0" encoding="UTF-8"?> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:obo_purl="http://purl.obolibrary.org/obo/" xmlns:owl="http://www.w3.org/2002/07/owl#" xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#" xmlns:oboinowl_gen="http://www.geneontology.org/formats/oboInOwl#" xmlns:metadata_def="http://data.bioontology.org/metadata/def/" xmlns:metadata="http://data.bioontology.org/metadata/" xmlns:dct="http://purl.org/dc/terms/"> <owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_4030033"> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000115"/> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0010008"/> <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_1000147"/> <rdfs:label>valve endothelial cell</rdfs:label> <rdfs:comment>At least in some mammalian species, a valve endothelial cell expresses CD31. Valve endothelial cells can undergo an endothelial to mesenchymal transition to acquire a fibroblast or myofibroblast phenotype that leads to changes in the microenvironmental signals and facilitates tissue regeneration.</rdfs:comment> <obo_purl:IAO_0000115>An endothelial cell that lines a surface of a cardiac valve leaflet. Along with valve interstitial cells, a valve endothelial cell maintains tissue homeostasis for the function of cardiac valves through secreting biochemical signals, matrix proteins and matrix remodeling enzymes.</obo_purl:IAO_0000115> <oboinowl_gen:hasExactSynonym>VEC</oboinowl_gen:hasExactSynonym> <oboinowl_gen:hasExactSynonym>valvular endothelial cell</oboinowl_gen:hasExactSynonym> <oboinowl_gen:inSubset rdf:resource="http://purl.obolibrary.org/obo/cl#human_subset"/> <oboinowl_gen:inSubset rdf:resource="http://purl.obolibrary.org/obo/cl#mouse_subset"/> <oboinowl_gen:inSubset rdf:resource="http://purl.obolibrary.org/obo/cl#cellxgene_subset"/> <metadata_def:prefLabel>valve endothelial cell</metadata_def:prefLabel> <metadata_def:mappingLoom>valveendothelialcell</metadata_def:mappingLoom> <metadata_def:mappingSameURI rdf:resource="http://purl.obolibrary.org/obo/CL_4030033"/> <metadata:prefixIRI>CL:4030033</metadata:prefixIRI> <dct:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2022-12-09T11:58:49Z</dct:date> </owl:Class> <rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_4030033"> <metadata_def:mappingSameURI rdf:resource="http://purl.obolibrary.org/obo/CL_4030033"/> </rdf:Description> </rdf:RDF>
<?xml version="1.0" encoding="UTF-8"?>
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    <obo_purl:IAO_0000115>An endothelial cell that lines a surface of a cardiac valve leaflet. Along with valve interstitial cells, a valve endothelial cell maintains tissue homeostasis for the function of cardiac valves through secreting biochemical signals, matrix proteins and matrix remodeling enzymes.</obo_purl:IAO_0000115>
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