GO:0008632

GO:0006917

Wikipedia:Apoptosis

A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.

GO:0006915

apoptotic programmed cell death

apoptotic cell death

programmed cell death by apoptosis

cell suicide

cellular suicide

biological_process

signaling (initiator) caspase activity

induction of apoptosis by p53

induction of apoptosis

apoptosis activator activity

caspase-dependent programmed cell death

commitment to apoptosis

GO:0006915

apoptotic process

activation of apoptosis

apoptosis

type I programmed cell death

apoptosis signaling

apoptotic program