Gene Ontology (GO)
OWL
Last submission date March 22, 2025
ID http://purl.obolibrary.org/obo/GO_0106344
http://purl.obolibrary.org/obo/GO_0106344
https://agroportal.lirmm.fr/ontologies/GO/GO_0106344
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Preferred name

4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP

Definitions
Catalysis of the reaction: 2 Fe(3+) + 4 H2O + L-histidyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] + N(6)-(pyridoxal phosphate)-L-lysyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] = (2S)-2-amino-5-hydroxy-4-oxopentanoyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] + 3-oxopropanoate + 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 2 Fe(2+) + 2 H+ + L-lysyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase].
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