Gene Ontology (GO)
OWL
Last submission date March 22, 2025
ID http://purl.obolibrary.org/obo/GO_0021732
http://purl.obolibrary.org/obo/GO_0021732
https://agroportal.lirmm.fr/ontologies/GO/GO_0021732
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Preferred name

midbrain-hindbrain boundary maturation

Synonyms
MHB maturation isthmus maturation
Definitions
A developmental process, independent of morphogenetic (shape) change, that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.
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