Gene Ontology (GO)
OWL
Last submission date March 22, 2025
ID http://purl.obolibrary.org/obo/GO_0021691
http://purl.obolibrary.org/obo/GO_0021691
https://agroportal.lirmm.fr/ontologies/GO/GO_0021691
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Preferred name

cerebellar Purkinje cell layer maturation

Definitions
A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar Purkinje cell layer to attain its fully functional state. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.
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