Preferred Name |
spleen |
Synonyms |
lien Entire spleen |
Definitions |
Organ found in virtually all vertebrate animals with important roles in regard to red blood cells and the immune system. In humans, it is located in the left upper quadrant of the abdomen. It removes old red blood cells and holds a reserve in case of hemorrhagic shock, especially in animals like horses (not in humans), while recycling iron. It synthesizes antibodies in its white pulp and removes, from blood and lymph node circulation, antibody-coated bacteria along with antibody-coated blood cells. Taxon notes: Neither hagfish nor lampreys possess what might be considered a discrete and condensed spleen. Hagfish possess dispersed lymphoid tissue within the submucosa of the intestine (96) associated with the portal vein (97), whereas lymphoid tissue is associated with the typhlosole portion of the intestine in lampreys (96) [PMID:20959416] the organ that functions to filter blood and to store red corpuscles and platelets |
ID |
http://purl.obolibrary.org/obo/UBERON_0002106 |
comment |
Taxon notes: Neither hagfish nor lampreys possess what might be considered a discrete and condensed spleen. Hagfish possess dispersed lymphoid tissue within the submucosa of the intestine (96) associated with the portal vein (97), whereas lymphoid tissue is associated with the typhlosole portion of the intestine in lampreys (96) [PMID:20959416] |
database_cross_reference |
MSH:D013154 EV:0100055 MIAA:0000085 SNOMEDCT:181279003 UMLS:C0037993 CALOHA:TS-0956 MA:0000141 GAID:1289 Wikipedia:Spleen MESH:A15.382.520.604.713 NCIT:C12432 http://upload.wikimedia.org/wikipedia/commons/d/d6/Illu_spleen.jpg OpenCyc:Mx4rvVjgw5wpEbGdrcN5Y29ycA http://upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Illu_spleen.jpg/200px-Illu_spleen.jpg VHOG:0000120 galen:Spleen FMA:7196 EMAPA:18767 MAT:0000085 TAO:0000436 EFO:0000869 XAO:0000328 BTO:0001281 ZFA:0000436 AAO:0010395 NCIt:C12432 http://www.snomedbrowser.com/Codes/Details/181279003 |
definition |
Organ found in virtually all vertebrate animals with important roles in regard to red blood cells and the immune system. In humans, it is located in the left upper quadrant of the abdomen. It removes old red blood cells and holds a reserve in case of hemorrhagic shock, especially in animals like horses (not in humans), while recycling iron. It synthesizes antibodies in its white pulp and removes, from blood and lymph node circulation, antibody-coated bacteria along with antibody-coated blood cells. the organ that functions to filter blood and to store red corpuscles and platelets |
depicted_by |
http://upload.wikimedia.org/wikipedia/commons/d/d6/Illu_spleen.jpg |
develops_from |
http://purl.obolibrary.org/obo/UBERON_0000945 |
external_definition |
An organ involved in red blood cell filtration and immune response.[AAO] |
has_exact_synonym |
lien Entire spleen |
has_obo_namespace |
uberon |
has_related_synonym |
lien |
has_relational_adjective |
splenic lienal |
homologous_in | |
homology_notes |
With the advent of clonal selection, the accumulation and segregation of T and B cells in specialized organs for antigen presentation became necessary, and indeed the spleen is found in all jawed vertebrates, but not in agnathans or invertebrates.[well established][VHOG] |
id |
UBERON:0002106 |
in_subset |
http://purl.obolibrary.org/obo/uberon#efo_slim http://purl.obolibrary.org/obo/uberon#vertebrate_core http://purl.obolibrary.org/obo/uberon/core#uberon_slim http://purl.obolibrary.org/obo/uberon/core#organ_slim http://purl.obolibrary.org/obo/uberon/core#pheno_slim http://purl.obolibrary.org/obo/uberon/core#efo_slim http://purl.obolibrary.org/obo/uberon#uberon_slim |
label |
spleen |
notation |
UBERON:0002106 |
part_of | |
prefLabel |
spleen |
taxon_notes |
In humans, it is located in the left upper quadrant of the abdomen. It removes old red blood cells and holds a reserve in case of hemorrhagic shock, especially in animals like horses (not in humans), while recycling iron Neither hagfish nor lampreys possess what might be considered a discrete and condensed spleen. Hagfish possess dispersed lymphoid tissue within the submucosa of the intestine (96) associated with the portal vein (97), whereas lymphoid tissue is associated with the typhlosole portion of the intestine in lampreys (96) |
treeView |
http://purl.obolibrary.org/obo/UBERON_0000945 http://purl.obolibrary.org/obo/UBERON_0000916 http://purl.obolibrary.org/obo/UBERON_0003061 |
UBPROP_0000009 |
It synthesizes antibodies in its white pulp and removes, from blood and lymph node circulation, antibody-coated bacteria along with antibody-coated blood cells |
subClassOf |
http://purl.obolibrary.org/obo/UBERON_0005057 http://purl.obolibrary.org/obo/UBERON_0004177 |
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