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ID	http://purl.obolibrary.org/obo/CHEBI_17203 http://purl.obolibrary.org/obo/CHEBI_17203 Loading
Preferred name	L-proline
Synonyms	PROLINE
Definitions	Pyrrolidine in which the pro-S hydrogen at position 2 is substituted by a carboxylic acid group. L-Proline is the only one of the twenty DNA-encoded amino acids which has a secondary amino group alpha to the carboxyl group. It is an essential component of collagen and is important for proper functioning of joints and tendons. It also helps maintain and strengthen heart muscles.

oboinowl_gen:hasAlternativeId	CHEBI:45040 CHEBI:42067 CHEBI:13154 CHEBI:45100 CHEBI:184637 CHEBI:6286 CHEBI:21373 CHEBI:45159
oboinowl_gen:inSubset	http://purl.obolibrary.org/obo/chebi#3_STAR
obo_purl:smiles	OC(=O)[C@@H]1CCCN1
obo_purl:charge	0
obo_purl:inchikey	ONIBWKKTOPOVIA-BYPYZUCNSA-N
oboinowl_gen:hasDbXref	MetaCyc:PRO MeSH:D011392 CiteXplore:17127472 PMID:16657874 KEGG DRUG:D00035 PMID:22770225 PMID:16668324 CiteXplore:19811425 KEGG COMPOUND:147-85-3 CiteXplore:16501220 HMDB:HMDB0000162 Beilstein:80810 CiteXplore:18802692 PMID:22475019 CiteXplore:22139509 CiteXplore:12770004 CiteXplore:22482728 CiteXplore:11076505 CiteXplore:16668324 CiteXplore:19656302 PMID:17127472 PMID:19580280 PMID:22451406 SNOMEDCT:52541003 KNApSAcK:C00001388 PMID:14975886 CiteXplore:18973300 PMID:16190672 PMID:16656443 PMID:22482728 PMID:12770004 PMID:15576824 CiteXplore:17608428 PMID:22201772 SNOMEDCT:421542006 CiteXplore:16656443 CiteXplore:19215998 PMID:22491679 CiteXplore:22201772 Drug_Central:4125 Gmelin:50152 CiteXplore:18551589 NCIt:C29612 PMID:22139509 CiteXplore:15576824 PMID:16033917 CiteXplore:15838615 PDBeChem:PRO PMID:18802692 Reaxys:80810 CiteXplore:16190672 HMDB:HMDB00162 CiteXplore:16033917 PMID:11076505 CiteXplore:22475019 PMID:18973300 KEGG:C00148 PMID:17608428 CiteXplore:15894682 PMID:19215998 CiteXplore:16657874 Wikipedia:L-proline PMID:15838615 KEGG:D00035 CiteXplore:19688381 PMID:19656302 PMID:15894682 KEGG COMPOUND:C00148 PMID:19811425 SNOMEDCT:257972000 CiteXplore:14975886 PMID:16501220 PMID:15973048 SNOMEDCT:421824005 CiteXplore:19580280 CiteXplore:15973048 CiteXplore:22491679 NIST Chemistry WebBook:147-85-3 CAS:147-85-3 CiteXplore:22451406 PMID:18551589 PMID:19688381 ChemIDplus:147-85-3 DrugBank:DB00172
obo_purl:IAO_0000115	Pyrrolidine in which the pro-S hydrogen at position 2 is substituted by a carboxylic acid group. L-Proline is the only one of the twenty DNA-encoded amino acids which has a secondary amino group alpha to the carboxyl group. It is an essential component of collagen and is important for proper functioning of joints and tendons. It also helps maintain and strengthen heart muscles.
skos:notation	CHEBI:17203
oboinowl_gen:hasExactSynonym	L-proline L-Proline
obo_purl:mass	115.13050
obo_purl:inchi	InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1
obo_purl:formula	C5H9NO2
oboinowl_gen:hasOBONamespace	chebi_ontology
rdf:type	http://www.w3.org/2002/07/owl#Class
oboinowl_gen:hasRelatedSynonym	PROLINE (2S)-pyrrolidine-2-carboxylic acid proline L-Prolin L-pyrrolidine-2-carboxylic acid 2-Pyrrolidinecarboxylic acid prolinum (S)-pyrrolidine-2-carboxylic acid L-(-)-proline (-)-proline (S)-2-carboxypyrrolidine (-)-2-pyrrolidinecarboxylic acid P (S)-2-pyrrolidinecarboxylic acid L-alpha-pyrrolidinecarboxylic acid prolina (-)-(S)-proline
oboinowl_gen:id	CHEBI:17203
rdfs:label	L-proline
obo_purl:monoisotopicmass	115.06333
rdfs:subClassOf	http://purl.obolibrary.org/obo/CHEBI_24532 http://purl.obolibrary.org/obo/CHEBI_33709

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