Experimental Factor Ontology (EFO)
OWL
Last submission date April 15, 2025
ID http://www.ebi.ac.uk/efo/EFO_0004838
http://www.ebi.ac.uk/efo/EFO_0004838
https://agroportal.lirmm.fr/ontologies/EFO/EFO_0004838
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Preferred name

calcium measurement

Synonyms
calcium levels
Definitions
Is a quantification of calcium, typically in serum. Calcium (Ca2+) plays a pivotal role in the physiology and biochemistry of organisms and the cell. It plays an important role in signal transduction pathways, where it acts as a second messenger, in neurotransmitter release from neurons, contraction of all muscle cell types, and fertilization. Many enzymes require calcium ions as a cofactor, those of the blood-clotting cascade being notable examples. Extracellular calcium is also important for maintaining the potential difference across excitable cell membranes, as well as proper bone formation.
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