Experimental Factor Ontology (EFO)
OWL
Last submission date March 29, 2025
ID http://purl.obolibrary.org/obo/GO_0005652
http://purl.obolibrary.org/obo/GO_0005652
https://agroportal.lirmm.fr/ontologies/EFO/GO_0005652
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Preferred name

nuclear lamina

Definitions
The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a cell nucleus, composed of lamin filaments. The polypeptides of the lamina are thought to be concerned in the dissolution of the nuclear envelope and its re-formation during mitosis. The lamina is composed of lamin A and lamin C filaments cross-linked into an orthogonal lattice, which is attached via lamin B to the inner nuclear membrane through interactions with a lamin B receptor, an IFAP, in the membrane.
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