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ID	http://purl.obolibrary.org/obo/CHEBI_64191 http://purl.obolibrary.org/obo/CHEBI_64191 https://agroportal.lirmm.fr/ontologies/EFO/CHEBI_64191 Loading
Preferred name	nafadotride
Synonyms	nafadotride N-[(1-butylpyrrolidin-2-yl)methyl]-4-cyano-1-methoxynaphthalene-2-carboxamide (+-)-nafadotride
Definitions	A naphthalenecarboxamide resulting from the formal condensation of the carboxylic acid group of 4-cyano-1-methoxynaphthalene-2-carboxylic acid with the primary amino group of 1-(1-butylpyrrolidin-2-yl]methanamine. It is a highly potent, competitive, preferential dopamine D3 receptor antagonist, centrally active upon systemic administration.

rdf:type	http://www.w3.org/2002/07/owl#Class Loading
rdfs:subClassOf	http://purl.obolibrary.org/obo/CHEBI_24532 Loading http://purl.obolibrary.org/obo/CHEBI_37622 Loading
rdfs:label	nafadotride
skos:notation	CHEBI:64191
obo_purl:IAO_0000115	A naphthalenecarboxamide resulting from the formal condensation of the carboxylic acid group of 4-cyano-1-methoxynaphthalene-2-carboxylic acid with the primary amino group of 1-(1-butylpyrrolidin-2-yl]methanamine. It is a highly potent, competitive, preferential dopamine D3 receptor antagonist, centrally active upon systemic administration.
oboinowl_gen:hasExactSynonym	nafadotride N-[(1-butylpyrrolidin-2-yl)methyl]-4-cyano-1-methoxynaphthalene-2-carboxamide
oboinowl_gen:hasDbXref	CAS:149649-22-9 ChEMBL:134432 ChemIDplus:149649-22-9 CiteXplore:8531087 CiteXplore:9252981 LINCS:LSM-1755 PMID:8531087 PMID:9252981 Reaxys:8356954 Wikipedia:Nafadotride MESH:C097285 See more See less
oboinowl_gen:hasOBONamespace	chebi_ontology
oboinowl_gen:id	CHEBI:64191
oboinowl_gen:inSubset	http://purl.obolibrary.org/obo/chebi#3_STAR Loading
has_role	http://www.ebi.ac.uk/efo/EFO_0001899 Loading
oboinowl_gen:hasRelatedSynonym	(+-)-nafadotride
obo_purl:charge	0
obo_purl:formula	C22H27N3O2
obo_purl:inchi	InChI=1S/C22H27N3O2/c1-3-4-11-25-12-7-8-17(25)15-24-22(26)20-13-16(14-23)18-9-5-6-10-19(18)21(20)27-2/h5-6,9-10,13,17H,3-4,7-8,11-12,15H2,1-2H3,(H,24,26)
obo_purl:inchikey	IDZASIQMRGPBCQ-UHFFFAOYSA-N
obo_purl:mass	365.46870
obo_purl:monoisotopicmass	365.21033
obo_purl:smiles	CCCCN1CCCC1CNC(=O)c1cc(C#N)c2ccccc2c1OC

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