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ID	http://purl.obolibrary.org/obo/CHEBI_28445 http://purl.obolibrary.org/obo/CHEBI_28445 https://agroportal.lirmm.fr/ontologies/EFO/CHEBI_28445 Loading
Preferred name	vincristine
Synonyms	22-oxovincaleukoblastine Vincristine (+)-Vincristine 22-Oxovincaleukoblastine 22-oxo-vincaleukoblastine leucristine leurocristine oncovin vincristin vinkristin See more See less
Definitions	A vinca alkaloid with formula C46H56N4O10 found in the Madagascar periwinkle, Catharanthus roseus. It is used (commonly as the corresponding sulfate salt)as a chemotherapy drug for the treatment of leukaemia, lymphoma, myeloma, breast cancer and head and neck cancer.

rdf:type	http://www.w3.org/2002/07/owl#Class Loading
rdfs:subClassOf	http://purl.obolibrary.org/obo/CHEBI_24532 Loading http://purl.obolibrary.org/obo/CHEBI_37622 Loading
rdfs:label	vincristine
skos:notation	CHEBI:28445
obo_purl:IAO_0000115	A vinca alkaloid with formula C46H56N4O10 found in the Madagascar periwinkle, Catharanthus roseus. It is used (commonly as the corresponding sulfate salt)as a chemotherapy drug for the treatment of leukaemia, lymphoma, myeloma, breast cancer and head and neck cancer.
oboinowl_gen:hasExactSynonym	22-oxovincaleukoblastine Vincristine
oboinowl_gen:hasDbXref	Beilstein:4779289 CAS:57-22-7 DrugBank:DB00541 Drug_Central:2825 HMDB:HMDB0014681 KEGG:C07204 KEGG:D08679 KNApSAcK:C00001783 MetaCyc:CPD-19894 NCIt:C933 PMID:18520608 PMID:30277559 PMID:30429697 PMID:30599272 PMID:30604513 PMID:30657998 PMID:31048222 PMID:31161774 PMID:31214762 PMID:31296986 SNOMEDCT:23079006 SNOMEDCT:387126006 Wikipedia:Vincristine MESH:D014750 See more See less
oboinowl_gen:hasOBONamespace	chebi_ontology
oboinowl_gen:id	CHEBI:28445
oboinowl_gen:inSubset	http://purl.obolibrary.org/obo/chebi#3_STAR Loading
has_role	http://purl.obolibrary.org/obo/CHEBI_35610 Loading
oboinowl_gen:hasRelatedSynonym	(+)-Vincristine 22-Oxovincaleukoblastine 22-oxo-vincaleukoblastine leucristine leurocristine oncovin vincristin vinkristin See more See less
oboinowl_gen:hasAlternativeId	CHEBI:27289 CHEBI:9987
obo_purl:charge	0
obo_purl:formula	C46H56N4O10
obo_purl:inchi	InChI=1S/C46H56N4O10/c1-7-42(55)22-28-23-45(40(53)58-5,36-30(14-18-48(24-28)25-42)29-12-9-10-13-33(29)47-36)32-20-31-34(21-35(32)57-4)50(26-51)38-44(31)16-19-49-17-11-15-43(8-2,37(44)49)39(60-27(3)52)46(38,56)41(54)59-6/h9-13,15,20-21,26,28,37-39,47,55-56H,7-8,14,16-19,22-25H2,1-6H3/t28-,37+,38-,39-,42+,43-,44-,45+,46+/m1/s1
obo_purl:inchikey	OGWKCGZFUXNPDA-XQKSVPLYSA-N
obo_purl:mass	824.95780
obo_purl:monoisotopicmass	824.39964
obo_purl:smiles	[H][C@@]12N3CC[C@@]11c4cc(c(OC)cc4N(C=O)[C@@]1([H])[C@](O)([C@H](OC(C)=O)[C@]2(CC)C=CC3)C(=O)OC)[C@]1(C[C@@H]2C[N@](CCc3c1[nH]c1ccccc31)C[C@](O)(CC)C2)C(=O)OC

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