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ID	http://purl.obolibrary.org/obo/CHEBI_27899 http://purl.obolibrary.org/obo/CHEBI_27899 https://agroportal.lirmm.fr/ontologies/EFO/CHEBI_27899 Loading
Preferred name	cisplatin
Synonyms	(SP-4-2)-diamminedichloridoplatinum (SP-4-2)-diamminedichloroplatinum Cisplatin cis-diamminedichloridoplatinum(II) cis-diamminedichloroplatinum(II) cisplatin Briplatin CDDP Cismaplat Lederplatin Neoplatin Peyrone's chloride Peyrone's salt Platamine Platinex Platinol Randa [PtCl2(NH3)2] cis-DDP cis-Diamminedichloroplatinum(II) cis-[PtCl2(NH3)2] cis-diamminedichloroplatinum cis-diammineplatinum(II) dichloride cis-dichlorodiammineplatinum(II) cis-platin cisplatine cisplatino cisplatinum See more See less
Definitions	A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a cis planar configuration around the central platinum ion. An anticancer drug that interacts with, and forms cross-links between, DNA and proteins, it is used as a neoplasm inhibitor to treat solid tumours, primarily of the testis and ovary. Commonly but incorrectly described as an alkylating agent due to its mechanism of action (but it lacks alkyl groups).

rdf:type	http://www.w3.org/2002/07/owl#Class Loading
rdfs:subClassOf	http://purl.obolibrary.org/obo/CHEBI_24431 Loading
rdfs:label	cisplatin
skos:notation	CHEBI:27899
obo_purl:IAO_0000115	A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a cis planar configuration around the central platinum ion. An anticancer drug that interacts with, and forms cross-links between, DNA and proteins, it is used as a neoplasm inhibitor to treat solid tumours, primarily of the testis and ovary. Commonly but incorrectly described as an alkylating agent due to its mechanism of action (but it lacks alkyl groups).
oboinowl_gen:hasExactSynonym	(SP-4-2)-diamminedichloridoplatinum (SP-4-2)-diamminedichloroplatinum Cisplatin cis-diamminedichloridoplatinum(II) cis-diamminedichloroplatinum(II)
oboinowl_gen:hasDbXref	CAS:15663-27-1 DrugBank:DB00515 Gmelin:2519 HMDB:HMDB0014656 KEGG:C06911 KEGG:D00275 MetaCyc:CPD0-1392 MolBase:25 PMID:10883661 PMID:12537968 PMID:12831510 PMID:12935404 PMID:16327988 PMID:18472761 PMID:1855275 PMID:23554447 PMID:23604226 PMID:23651576 PMID:28494534 Patent:DE2318020 Patent:DE2329485 Reaxys:11324567 Wikipedia:Cisplatin ChEMBL:428069 ChemIDplus:15663-27-1 KEGG COMPOUND:15663-27-1 KEGG COMPOUND:C06911 KEGG DRUG:D00275 MeSH:D002945 NCIt:C376 SNOMEDCT:387318005 SNOMEDCT:57066004 See more See less
oboinowl_gen:hasOBONamespace	chebi_ontology
oboinowl_gen:id	CHEBI:27899
oboinowl_gen:inSubset	http://purl.obolibrary.org/obo/chebi#3_STAR Loading
oboinowl_gen:hasRelatedSynonym	cisplatin Briplatin CDDP Cismaplat Lederplatin Neoplatin Peyrone's chloride Peyrone's salt Platamine Platinex Platinol Randa [PtCl2(NH3)2] cis-DDP cis-Diamminedichloroplatinum(II) cis-[PtCl2(NH3)2] cis-diamminedichloroplatinum cis-diammineplatinum(II) dichloride cis-dichlorodiammineplatinum(II) cis-platin cisplatine cisplatino cisplatinum See more See less
oboinowl_gen:hasAlternativeId	CHEBI:23314 CHEBI:3722
obo_purl:charge	0
obo_purl:formula	Cl2H6N2Pt H6Cl2N2Pt
obo_purl:inchi	InChI=1S/2ClH.2H3N.Pt/h21H;21H3;/q;;;;+2/p-2
obo_purl:inchikey	LXZZYRPGZAFOLE-UHFFFAOYSA-L
obo_purl:mass	300.04452
obo_purl:monoisotopicmass	298.95560
obo_purl:smiles	[H][N]([H])([H])[Pt](Cl)(Cl)[N]([H])([H])[H]

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