Experimental Factor Ontology

Last uploaded: July 4, 2019
Preferred Name

cerebral cortex

Synonyms

cortex cerebralis

pallium of the brain

cortical plate (areas)

cortex of cerebral hemisphere

cortical plate (CTXpl)

Entire cerebral cortex

brain cortex

cortex cerebri

Definitions

This class was created automatically from a combination of ontologies The cerebral cortex is a structure within the brain that plays a key role in memory, attention, perceptual awareness, thought, language, and consciousness. It constitutes the outermost layer of the cerebrum. In preserved brains, it has a grey color, hence the name 'grey matter'. Grey matter is formed by neurons and their unmyelinated fibers, whereas the white matter below the grey matter of the cortex is formed predominantly by myelinated axons interconnecting different regions of the central nervous system. The human cerebral cortex is 2–4 mm (0.08–0.16 inches) thick. The surface of the cerebral cortex is folded in large mammals, such that more than two-thirds of the cortical surface is buried in the grooves, called 'sulci. ' The phylogenetically most recent part of the cerebral cortex, the neocortex, also called isocortex, is differentiated into six horizontal layers; the more ancient part of the cerebral cortex, the hippocampus (also called archicortex), has at most three cellular layers, and is divided into subfields. Relative variations in thickness or cell type (among other parameters) allow us to distinguish between different neocortical architectonic fields. The geometry of at least some of these fields seems to be related to the anatomy of the cortical folds, and, for example, layers in the upper part of the cortical ridges seem to be more clearly differentiated than in its deeper parts. [WP,unvetted]. The thin layer of gray matter on the surface of the cerebral hemisphere that develops from the telencephalon. It consists of the neocortex (6 layered cortex or isocortex), the hippocampal formation and the olfactory cortex.

ID

http://purl.obolibrary.org/obo/UBERON_0000956

comment

This class was created automatically from a combination of ontologies

curator note

We follow NIFSTD in defining cerebral cortex and including both neocortex and hippocampal formation (DG+hippocampus).

database_cross_reference

http://upload.wikimedia.org/wikipedia/commons/thumb/7/7b/Cerebral_Cortex_location.jpg/200px-Cerebral_Cortex_location.jpg

MBA:688

http://upload.wikimedia.org/wikipedia/commons/9/9a/Brainmaps-macaque-hippocampus.jpg

MSH:D002540

EMAPA:17544

Wikipedia:Cerebral_cortex

FMA:61830

MESH:A08.186.211.730.885.213

BM:Tel-Cx

EV:0100166

MA:0000185

UMLS:C0007776

GAID:629

VHOG:0000722

NCIt:C12443

DHBA:10159

EFO:0000328

NIF_GrossAnatomy:birnlex_1494

NCIT:C12443

HBA:4008

BTO:0000233

BAMS:C

MIAA:0000108

http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=39

MAT:0000108

BAMS:Cx

PBA:128011354

SNOMEDCT:362880003

BAMS:CTX

CALOHA:TS-0091

ABA:CTX

BAMS:Cerebral_cortex

EHDAA:5464

EHDAA2:0000234

http://uri.neuinfo.org/nif/nifstd/birnlex_1494

http://en.wikipedia.org/wiki/Cerebral_cortex

http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=39

http://www.snomedbrowser.com/Codes/Details/362880003

http://linkedlifedata.com/resource/umls/id/C0007776

definition

The cerebral cortex is a structure within the brain that plays a key role in memory, attention, perceptual awareness, thought, language, and consciousness. It constitutes the outermost layer of the cerebrum. In preserved brains, it has a grey color, hence the name 'grey matter'. Grey matter is formed by neurons and their unmyelinated fibers, whereas the white matter below the grey matter of the cortex is formed predominantly by myelinated axons interconnecting different regions of the central nervous system. The human cerebral cortex is 2–4 mm (0.08–0.16 inches) thick. The surface of the cerebral cortex is folded in large mammals, such that more than two-thirds of the cortical surface is buried in the grooves, called 'sulci. ' The phylogenetically most recent part of the cerebral cortex, the neocortex, also called isocortex, is differentiated into six horizontal layers; the more ancient part of the cerebral cortex, the hippocampus (also called archicortex), has at most three cellular layers, and is divided into subfields. Relative variations in thickness or cell type (among other parameters) allow us to distinguish between different neocortical architectonic fields. The geometry of at least some of these fields seems to be related to the anatomy of the cortical folds, and, for example, layers in the upper part of the cortical ridges seem to be more clearly differentiated than in its deeper parts. [WP,unvetted].

The thin layer of gray matter on the surface of the cerebral hemisphere that develops from the telencephalon. It consists of the neocortex (6 layered cortex or isocortex), the hippocampal formation and the olfactory cortex.

depicted_by

http://upload.wikimedia.org/wikipedia/commons/7/7b/Cerebral_Cortex_location.jpg

http://upload.wikimedia.org/wikipedia/commons/9/9a/Brainmaps-macaque-hippocampus.jpg

external_definition

The cerebral cortex is a structure within the brain that plays a key role in memory, attention, perceptual awareness, thought, language, and consciousness. It constitutes the outermost layer of the cerebrum. In preserved brains, it has a grey color, hence the name 'grey matter'. Grey matter is formed by neurons and their unmyelinated fibers, whereas the white matter below the grey matter of the cortex is formed predominantly by myelinated axons interconnecting different regions of the central nervous system. The human cerebral cortex is 2-4 mm (0.08-0.16 inches) thick. The surface of the cerebral cortex is folded in large mammals, such that more than two-thirds of the cortical surface is buried in the grooves, called 'sulci. ' The phylogenetically most recent part of the cerebral cortex, the neocortex, also called isocortex, is differentiated into six horizontal layers; the more ancient part of the cerebral cortex, the hippocampus (also called archicortex), has at most three cellular layers, and is divided into subfields. Relative variations in thickness or cell type (among other parameters) allow us to distinguish between different neocortical architectonic fields. The geometry of at least some of these fields seems to be related to the anatomy of the cortical folds, and, for example, layers in the upper part of the cortical ridges seem to be more clearly differentiated than in its deeper parts. [WP,unvetted][Wikipedia:Cerebral_cortex].

has_exact_synonym

pallium of the brain

cortex of cerebral hemisphere

Entire cerebral cortex

brain cortex

cortex cerebri

has_obo_namespace

uberon

has_related_synonym

cortex cerebralis

pallium of the brain

cortical plate (areas)

cortical plate (CTXpl)

brain cortex

cortex cerebri

homologous_in

http://purl.obolibrary.org/obo/NCBITaxon_7742

homology_notes

Migration of neurons from the basal or striatal portions of the anterior part of the neural tube occurs to varying degrees in different vertebrate classes, but a true cerebral cortex is generally acknowledged to have made its first appearance in reptiles. The definition can be unambiguous, since 'cortex' simply implies the existence of a surface neuronal layer with an overlying 'zonal lamina' or 'molecular' layer containing dendrites and axons, which is separated from the underlying basal 'matrix' by white matter. Although reptilian cerebral cortex does indeed fulfill these conditions in certain locations, the separation from striatal structures is often indistinct, so that it may even be argued that some primitive dipnoans possess a pallium or cortex. Nevertheless, an extensive laminated layer separated by underlying white matter is well represented only in reptiles and mammals.[well established][VHOG]

id

UBERON:0000956

in_subset

http://purl.obolibrary.org/obo/uberon#efo_slim

http://purl.obolibrary.org/obo/uberon/core#uberon_slim

http://purl.obolibrary.org/obo/uberon/core#pheno_slim

http://purl.obolibrary.org/obo/uberon/core#efo_slim

http://purl.obolibrary.org/obo/uberon#uberon_slim

label

cerebral cortex

notation

UBERON:0000956

part_of

http://purl.obolibrary.org/obo/UBERON_0001869

prefLabel

cerebral cortex

RO_0002175

http://purl.obolibrary.org/obo/NCBITaxon_117569

taxon_notes

hagfishes have independently evolved a highly laminated cerebral cortex, comparable in many ways to the cerebral cortex of mammals [http://icb.oxfordjournals.org/content/42/4/743]

treeView

http://purl.obolibrary.org/obo/UBERON_0001869

subClassOf

http://purl.obolibrary.org/obo/UBERON_0000061

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Internal mappings

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http://purl.obolibrary.org/obo/UBERON_0000956 Cell Ontology LOOM
http://purl.obolibrary.org/obo/UBERON_0000956 Cell Ontology SAME_URI
http://lod.nal.usda.gov/nalt/24050 National Agricultural Library Thesaurus LOOM
http://www.yso.fi/onto/yso/p7039 Agriculture and Forestry Ontology LOOM
http://id.agrisemantics.org/gacs/C24636 Global Agricultural Concept Scheme LOOM

Interportal mappings

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http://purl.obolibrary.org/obo/BTO_0000233 http://bioportal.bioontology.org/ontologies/BTO REST EFO http://www.geneontology.org/formats/oboinowl#hasdbxref

External mappings

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There are currently no external mappings for this class.