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ID	http://purl.obolibrary.org/obo/CHEBI_2668 http://purl.obolibrary.org/obo/CHEBI_2668 https://agroportal.lirmm.fr/ontologies/ECTO/CHEBI_2668 Loading
Preferred name	amlodipine
Synonyms	amlodipinum 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate amlodipine amlodipino 3-Ethyl-5-methyl (+-)-2-(2-aminoethoxymethyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate Amlodipine Free Base
Definitions	A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.

obo_purl:RO_0000053	http://purl.obolibrary.org/obo/CHEBI_38215 http://purl.obolibrary.org/obo/CHEBI_35674 http://purl.obolibrary.org/obo/CHEBI_35620
oboinowl_gen:inSubset	http://purl.obolibrary.org/obo/chebi#3_STAR
obo_purl:smiles	CCOC(=O)C1=C(COCCN)NC(C)=C(C1c1ccccc1Cl)C(=O)OC
obo_purl:charge	0
obo_purl:inchikey	HTIQEAQVCYTUBX-UHFFFAOYSA-N
obo_purl:RO_0000087	http://purl.obolibrary.org/obo/CHEBI_38215 http://purl.obolibrary.org/obo/CHEBI_35674 http://purl.obolibrary.org/obo/CHEBI_35620
oboinowl_gen:hasDbXref	PMID:16422032 DrugBank:DB00381 Reaxys:3570229 PMID:19450066 PMID:9156957 Patent:US4572909 Beilstein:3570229 PMID:8310972 LINCS:LSM-1388 PMID:7522286 VSDB:2963 PMID:1834846 CAS:88150-42-9 PMID:1532771 PMID:8310973 KEGG:C06825 Patent:EP89167 PMID:21591999 Drug_Central:183 KEGG:D07450 Wikipedia:Amlodipine
obo_purl:IAO_0000115	A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.
skos:notation	CHEBI:2668
oboinowl_gen:hasExactSynonym	3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
obo_purl:mass	408.87600
obo_purl:inchi	InChI=1S/C20H25ClN2O5/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h5-8,17,23H,4,9-11,22H2,1-3H3
obo_purl:formula	C20H25ClN2O5
oboinowl_gen:hasOBONamespace	chebi_ontology
rdf:type	http://www.w3.org/2002/07/owl#Class
oboinowl_gen:hasRelatedSynonym	amlodipinum amlodipine amlodipino 3-Ethyl-5-methyl (+-)-2-(2-aminoethoxymethyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate Amlodipine Free Base
oboinowl_gen:id	CHEBI:2668
rdfs:label	amlodipine
obo_purl:monoisotopicmass	408.14520
rdfs:subClassOf	http://purl.obolibrary.org/obo/CHEBI_23990 http://purl.obolibrary.org/obo/CHEBI_50994 http://purl.obolibrary.org/obo/CHEBI_83403 http://purl.obolibrary.org/obo/CHEBI_25248 http://purl.obolibrary.org/obo/CHEBI_50075

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